iGMDRD42
Standard Name | CHEMBL | Pubchem CID | DRUGBANK ID | Drug Status | Drug targets (TTD) | Drug Type |
---|---|---|---|---|---|---|
Vorinostat | CHEMBL98 | 5311 | DB02546 | Alone | DAP001082 | Small Molecule |
Drug Class:
AminesAntineoplastic AgentsAntineoplastic and Immunomodulating AgentsCarboxylic AcidsEnzyme InhibitorsFluorine RadioisotopesHistone Deacetylase InhibitorsHydroxy AcidsHydroxylaminesHyperglycemia-Associated AgentsImmunosuppressive AgentsMyelosuppressive AgentsPotential QTc-Prolonging AgentsQTc Prolonging AgentsDrug Pathways:
Chromatin histone acetylationDrug-model tissue-cancer distribution: Bubble Plot
Drug-gene pathway enrichments
Drug-gene GO enrichments
Drug-Gene: Aster Plot
Gene ID | Gene Name | Model Num. |
---|---|---|
3696 | ITGB8 | 1 |
7074 | TIAM1 | 4 |
7837 | PXDN | 3 |
567 | B2M | 1 |
1464 | CSPG4 | 3 |
10641 | NPRL2 | 5 |
4926 | NUMA1 | 2 |
2200 | FBN1 | 3 |
399 | RHOH | 3 |
9706 | ULK2 | 1 |
3845 | KRAS | 1 |
5295 | PIK3R1 | 1 |
23097 | CDK19 | 3 |
8289 | ARID1A | 3 |
8266 | UBL4A | 1 |
5593 | PRKG2 | 3 |
6938 | TCF12 | 2 |
390502 | SERPINA2 | 4 |
64783 | RBM15 | 1 |
4172 | MCM3 | 1 |
3066 | HDAC2 | 1 |
5298 | PI4KB | 1 |
55252 | ASXL2 | 1 |
577 | ADGRB3 | 4 |
1387 | CREBBP | 2 |
11200 | CHEK2 | 1 |
9048 | ARTN | 5 |
5596 | MAPK4 | 2 |
1111 | CHEK1 | 1 |
10438 | C1D | 2 |
11122 | PTPRT | 5 |
5159 | PDGFRB | 3 |
7173 | TPO | 2 |
4851 | NOTCH1 | 1 |
7158 | TP53BP1 | 1 |
25937 | WWTR1 | 1 |
3621 | ING1 | 6 |
8313 | AXIN2 | 3 |
11169 | WDHD1 | 3 |
5601 | MAPK9 | 1 |
3688 | ITGB1 | 9 |
2045 | EPHA7 | 3 |
2064 | ERBB2 | 7 |
983 | CDK1 | 1 |
6850 | SYK | 1 |
1456 | CSNK1G3 | 2 |
5580 | PRKCD | 3 |
92 | ACVR2A | 1 |
7525 | YES1 | 3 |
6709 | SPTAN1 | 2 |
50488 | MINK1 | 1 |
6464 | SHC1 | 2 |
2778 | GNAS | 3 |
9590 | AKAP12 | 3 |
575 | ADGRB1 | 3 |
9096 | TBX18 | 6 |
7533 | YWHAH | 2 |
5327 | PLAT | 7 |
10413 | YAP1 | 1 |
2201 | FBN2 | 2 |
9794 | MAML1 | 3 |
57523 | NYNRIN | 3 |
28514 | DLL1 | 1 |
58508 | KMT2C | 2 |
7157 | TP53 | 1 |
6092 | ROBO2 | 3 |
3673 | ITGA2 | 1 |
6794 | STK11 | 1 |
3791 | KDR | 1 |
147746 | HIPK4 | 3 |
1019 | CDK4 | 2 |
1102 | RCBTB2 | 2 |
9088 | PKMYT1 | 3 |
57591 | MRTFA | 4 |
136332 | LRGUK | 2 |
4436 | MSH2 | 2 |
9401 | RECQL4 | 3 |
10422 | UBAC1 | 1 |
10499 | NCOA2 | 3 |
8997 | KALRN | 5 |
7994 | KAT6A | 5 |
57111 | RAB25 | 1 |
4089 | SMAD4 | 2 |
3559 | IL2RA | 4 |
672 | BRCA1 | 1 |
285220 | EPHA6 | 3 |
2047 | EPHB1 | 2 |
8216 | LZTR1 | 1 |
4214 | MAP3K1 | 2 |
3702 | ITK | 4 |
440275 | EIF2AK4 | 3 |
602 | BCL3 | 2 |
8202 | NCOA3 | 2 |
253260 | RICTOR | 3 |
2318 | FLNC | 2 |
4803 | NGF | 4 |
7075 | TIE1 | 2 |
1956 | EGFR | 4 |
841 | CASP8 | 3 |
4609 | MYC | 1 |
11064 | CNTRL | 2 |
5789 | PTPRD | 2 |
8013 | NR4A3 | 3 |
26278 | SACS | 6 |
6446 | SGK1 | 1 |
5592 | PRKG1 | 3 |
7917 | BAG6 | 3 |
27330 | RPS6KA6 | 3 |
22976 | PAXIP1 | 3 |
120892 | LRRK2 | 2 |
89795 | NAV3 | 4 |
694 | BTG1 | 5 |
2113 | ETS1 | 1 |
8029 | CUBN | 5 |
11184 | MAP4K1 | 2 |
5128 | CDK17 | 2 |
2767 | GNA11 | 4 |
1024 | CDK8 | 3 |
8491 | MAP4K3 | 3 |
4853 | NOTCH2 | 1 |
1230 | CCR1 | 3 |
23598 | PATZ1 | 3 |
23742 | NPAP1 | 6 |
1869 | E2F1 | 3 |
667 | DST | 1 |
140803 | TRPM6 | 2 |
2188 | FANCF | 3 |
2648 | KAT2A | 1 |
2277 | VEGFD | 3 |
5887 | RAD23B | 1 |
3161 | HMMR | 3 |
55561 | CDC42BPG | 3 |
8821 | INPP4B | 1 |
10243 | GPHN | 3 |
4297 | KMT2A | 2 |
4619 | MYH1 | 4 |
9021 | SOCS3 | 2 |
9223 | MAGI1 | 2 |
5395 | PMS2 | 3 |
53353 | LRP1B | 5 |
9659 | PDE4DIP | 3 |
3624 | INHBA | 3 |
2194 | FASN | 3 |
598 | BCL2L1 | 3 |
3579 | CXCR2 | 7 |
5111 | PCNA | 1 |
23380 | SRGAP2 | 1 |
5170 | PDPK1 | 1 |
22982 | DIP2C | 2 |
7099 | TLR4 | 3 |
3709 | ITPR2 | 3 |
6194 | RPS6 | 1 |
100862685 | ERVK-19 | 1 |
51562 | MBIP | 2 |
6777 | STAT5B | 1 |
84072 | HORMAD1 | 2 |
5054 | SERPINE1 | 1 |
9894 | TELO2 | 3 |
5925 | RB1 | 3 |
1857 | DVL3 | 1 |
5567 | PRKACB | 2 |
54518 | APBB1IP | 3 |
8814 | CDKL1 | 3 |
4613 | MYCN | 1 |
494551 | WEE2 | 3 |
4629 | MYH11 | 3 |
23112 | TNRC6B | 1 |
1803 | DPP4 | 1 |
1499 | CTNNB1 | 1 |
2892 | GRIA3 | 2 |
1795 | DOCK3 | 3 |
5624 | PROC | 2 |
5970 | RELA | 2 |
Gene in drug-gene network: Network Plot
![](image/drug_network_legends.png)
Models in Vorinostat