iGMDRD42
| Standard Name | CHEMBL | Pubchem CID | DRUGBANK ID | Drug Status | Drug targets (TTD) | Drug Type |
|---|---|---|---|---|---|---|
| Vorinostat | CHEMBL98 | 5311 | DB02546 | Alone | DAP001082 | Small Molecule |
Drug Class:
AminesAntineoplastic AgentsAntineoplastic and Immunomodulating AgentsCarboxylic AcidsEnzyme InhibitorsFluorine RadioisotopesHistone Deacetylase InhibitorsHydroxy AcidsHydroxylaminesHyperglycemia-Associated AgentsImmunosuppressive AgentsMyelosuppressive AgentsPotential QTc-Prolonging AgentsQTc Prolonging AgentsDrug Pathways:
Chromatin histone acetylationDrug-model tissue-cancer distribution: Bubble Plot
Drug-gene pathway enrichments
Drug-gene GO enrichments
Drug-Gene: Aster Plot
| Gene ID | Gene Name | Model Num. |
|---|---|---|
| 3696 | ITGB8 | 1 |
| 7074 | TIAM1 | 4 |
| 7837 | PXDN | 3 |
| 567 | B2M | 1 |
| 1464 | CSPG4 | 3 |
| 10641 | NPRL2 | 5 |
| 4926 | NUMA1 | 2 |
| 2200 | FBN1 | 3 |
| 399 | RHOH | 3 |
| 9706 | ULK2 | 1 |
| 3845 | KRAS | 1 |
| 5295 | PIK3R1 | 1 |
| 23097 | CDK19 | 3 |
| 8289 | ARID1A | 3 |
| 8266 | UBL4A | 1 |
| 5593 | PRKG2 | 3 |
| 6938 | TCF12 | 2 |
| 390502 | SERPINA2 | 4 |
| 64783 | RBM15 | 1 |
| 4172 | MCM3 | 1 |
| 3066 | HDAC2 | 1 |
| 5298 | PI4KB | 1 |
| 55252 | ASXL2 | 1 |
| 577 | ADGRB3 | 4 |
| 1387 | CREBBP | 2 |
| 11200 | CHEK2 | 1 |
| 9048 | ARTN | 5 |
| 5596 | MAPK4 | 2 |
| 1111 | CHEK1 | 1 |
| 10438 | C1D | 2 |
| 11122 | PTPRT | 5 |
| 5159 | PDGFRB | 3 |
| 7173 | TPO | 2 |
| 4851 | NOTCH1 | 1 |
| 7158 | TP53BP1 | 1 |
| 25937 | WWTR1 | 1 |
| 3621 | ING1 | 6 |
| 8313 | AXIN2 | 3 |
| 11169 | WDHD1 | 3 |
| 5601 | MAPK9 | 1 |
| 3688 | ITGB1 | 9 |
| 2045 | EPHA7 | 3 |
| 2064 | ERBB2 | 7 |
| 983 | CDK1 | 1 |
| 6850 | SYK | 1 |
| 1456 | CSNK1G3 | 2 |
| 5580 | PRKCD | 3 |
| 92 | ACVR2A | 1 |
| 7525 | YES1 | 3 |
| 6709 | SPTAN1 | 2 |
| 50488 | MINK1 | 1 |
| 6464 | SHC1 | 2 |
| 2778 | GNAS | 3 |
| 9590 | AKAP12 | 3 |
| 575 | ADGRB1 | 3 |
| 9096 | TBX18 | 6 |
| 7533 | YWHAH | 2 |
| 5327 | PLAT | 7 |
| 10413 | YAP1 | 1 |
| 2201 | FBN2 | 2 |
| 9794 | MAML1 | 3 |
| 57523 | NYNRIN | 3 |
| 28514 | DLL1 | 1 |
| 58508 | KMT2C | 2 |
| 7157 | TP53 | 1 |
| 6092 | ROBO2 | 3 |
| 3673 | ITGA2 | 1 |
| 6794 | STK11 | 1 |
| 3791 | KDR | 1 |
| 147746 | HIPK4 | 3 |
| 1019 | CDK4 | 2 |
| 1102 | RCBTB2 | 2 |
| 9088 | PKMYT1 | 3 |
| 57591 | MRTFA | 4 |
| 136332 | LRGUK | 2 |
| 4436 | MSH2 | 2 |
| 9401 | RECQL4 | 3 |
| 10422 | UBAC1 | 1 |
| 10499 | NCOA2 | 3 |
| 8997 | KALRN | 5 |
| 7994 | KAT6A | 5 |
| 57111 | RAB25 | 1 |
| 4089 | SMAD4 | 2 |
| 3559 | IL2RA | 4 |
| 672 | BRCA1 | 1 |
| 285220 | EPHA6 | 3 |
| 2047 | EPHB1 | 2 |
| 8216 | LZTR1 | 1 |
| 4214 | MAP3K1 | 2 |
| 3702 | ITK | 4 |
| 440275 | EIF2AK4 | 3 |
| 602 | BCL3 | 2 |
| 8202 | NCOA3 | 2 |
| 253260 | RICTOR | 3 |
| 2318 | FLNC | 2 |
| 4803 | NGF | 4 |
| 7075 | TIE1 | 2 |
| 1956 | EGFR | 4 |
| 841 | CASP8 | 3 |
| 4609 | MYC | 1 |
| 11064 | CNTRL | 2 |
| 5789 | PTPRD | 2 |
| 8013 | NR4A3 | 3 |
| 26278 | SACS | 6 |
| 6446 | SGK1 | 1 |
| 5592 | PRKG1 | 3 |
| 7917 | BAG6 | 3 |
| 27330 | RPS6KA6 | 3 |
| 22976 | PAXIP1 | 3 |
| 120892 | LRRK2 | 2 |
| 89795 | NAV3 | 4 |
| 694 | BTG1 | 5 |
| 2113 | ETS1 | 1 |
| 8029 | CUBN | 5 |
| 11184 | MAP4K1 | 2 |
| 5128 | CDK17 | 2 |
| 2767 | GNA11 | 4 |
| 1024 | CDK8 | 3 |
| 8491 | MAP4K3 | 3 |
| 4853 | NOTCH2 | 1 |
| 1230 | CCR1 | 3 |
| 23598 | PATZ1 | 3 |
| 23742 | NPAP1 | 6 |
| 1869 | E2F1 | 3 |
| 667 | DST | 1 |
| 140803 | TRPM6 | 2 |
| 2188 | FANCF | 3 |
| 2648 | KAT2A | 1 |
| 2277 | VEGFD | 3 |
| 5887 | RAD23B | 1 |
| 3161 | HMMR | 3 |
| 55561 | CDC42BPG | 3 |
| 8821 | INPP4B | 1 |
| 10243 | GPHN | 3 |
| 4297 | KMT2A | 2 |
| 4619 | MYH1 | 4 |
| 9021 | SOCS3 | 2 |
| 9223 | MAGI1 | 2 |
| 5395 | PMS2 | 3 |
| 53353 | LRP1B | 5 |
| 9659 | PDE4DIP | 3 |
| 3624 | INHBA | 3 |
| 2194 | FASN | 3 |
| 598 | BCL2L1 | 3 |
| 3579 | CXCR2 | 7 |
| 5111 | PCNA | 1 |
| 23380 | SRGAP2 | 1 |
| 5170 | PDPK1 | 1 |
| 22982 | DIP2C | 2 |
| 7099 | TLR4 | 3 |
| 3709 | ITPR2 | 3 |
| 6194 | RPS6 | 1 |
| 100862685 | ERVK-19 | 1 |
| 51562 | MBIP | 2 |
| 6777 | STAT5B | 1 |
| 84072 | HORMAD1 | 2 |
| 5054 | SERPINE1 | 1 |
| 9894 | TELO2 | 3 |
| 5925 | RB1 | 3 |
| 1857 | DVL3 | 1 |
| 5567 | PRKACB | 2 |
| 54518 | APBB1IP | 3 |
| 8814 | CDKL1 | 3 |
| 4613 | MYCN | 1 |
| 494551 | WEE2 | 3 |
| 4629 | MYH11 | 3 |
| 23112 | TNRC6B | 1 |
| 1803 | DPP4 | 1 |
| 1499 | CTNNB1 | 1 |
| 2892 | GRIA3 | 2 |
| 1795 | DOCK3 | 3 |
| 5624 | PROC | 2 |
| 5970 | RELA | 2 |
Gene in drug-gene network: Network Plot
Models in Vorinostat
CLASSFICATION
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