YES1
Summary: This gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. This gene lies in close proximity to thymidylate synthase gene on chromosome 18, and a corresponding pseudogene has been found on chromosome 22. [provided by RefSeq, Jul 2008].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
OMIM IDMIM:164880 Ensembl IDEnsembl:ENSG00000176105 HGNC IDHGNC:HGNC:12841 PHARMGKB IDPA37432 Map Location18p11.32 |
GO terms in YES1
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Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
CC | IDA | GO:0005794 | Golgi apparatus |
CC | IEA | GO:0005815 | microtubule organizing center |
CC | IDA | GO:0005829 | cytosol |
CC | TAS | GO:0005829 | cytosol |
CC | IEA | GO:0005884 | actin filament |
CC | IDA | GO:0005886 | plasma membrane |
Gene expression in normal tissue: YES1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in YES1
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Database | Pathway ID | Pathway Des. |
---|---|---|
pid | alphasynuclein_pathway | Alpha-synuclein signaling |
pid | cdc42_pathway | CDC42 signaling events |
pid | cxcr4_pathway | CXCR4-mediated signaling events |
pid | epha_fwdpathway | EPHA forward signaling |
pid | ephrinbrevpathway | Ephrin B reverse signaling |
pid | fak_pathway | Signaling events mediated by focal adhesion kinase |
Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot

Gene-drug targets distribution
Gene Structure: PDB
Models in YES1
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
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No matching records found |