YES1


Summary: This gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. This gene lies in close proximity to thymidylate synthase gene on chromosome 18, and a corresponding pseudogene has been found on chromosome 22. [provided by RefSeq, Jul 2008].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location

GO terms in YES1


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Term Type
Evidence Type
GO Term ID
GO Des.
CC IDA GO:0005794 Golgi apparatus
CC IEA GO:0005815 microtubule organizing center
CC IDA GO:0005829 cytosol
CC TAS GO:0005829 cytosol
CC IEA GO:0005884 actin filament
CC IDA GO:0005886 plasma membrane
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Gene expression in normal tissue: YES1

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in YES1


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Database
Pathway ID
Pathway Des.
pid alphasynuclein_pathway Alpha-synuclein signaling
pid cdc42_pathway CDC42 signaling events
pid cxcr4_pathway CXCR4-mediated signaling events
pid epha_fwdpathway EPHA forward signaling
pid ephrinbrevpathway Ephrin B reverse signaling
pid fak_pathway Signaling events mediated by focal adhesion kinase
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD144 NSC95397 5
iGMDRD150 RITA 2
iGMDRD152 179324-69-7 3
iGMDRD61 Kinetin riboside 6
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in YES1

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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