LRGUK
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| leucine rich repeats and guanylate kinase domain containing | MIM:616478 | Ensembl:ENSG00000155530 | HGNC:HGNC:21964 | PA162394330 | 7q33 |
Gene Categories:
KINASEGO terms in LRGUK
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | ISS | GO:0001669 | acrosomal vesicle |
| CC | ISS | GO:0002177 | manchette |
| CC | IBA | GO:0005829 | cytosol |
| CC | IEA | GO:0042995 | cell projection |
| BP | ISS | GO:0007283 | spermatogenesis |
| BP | IEA | GO:0016310 | phosphorylation |
| BP | IEA | GO:0030154 | cell differentiation |
| BP | ISS | GO:0035082 | axoneme assembly |
| MF | IBA | GO:0004385 | guanylate kinase activity |
| MF | IEA | GO:0005524 | ATP binding |
| MF | IEA | GO:0016301 | kinase activity |
Gene expression in normal tissue: LRGUK
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in LRGUK
| Database | Pathway ID | Pathway Des. |
|---|
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD82 | Quiflapon | 2 |
| iGMDRD42 | Vorinostat | 2 |
| iGMDRD505 | Pevonedistat | 5 |
| iGMDRD246 | NPC26 | 3 |
| iGMDRD329 | Merck60 | 3 |
| iGMDRD662 | JQ-1 | 3 |
| iGMDRD414 | MST-312 | 3 |
| iGMDRD871 | BRD6368 | 2 |
| iGMDRD267 | Oligomycin A | 1 |
| iGMDRD705 | Nakiterpiosin | 4 |
| iGMDRD105 | Triptolide | 2 |
| iGMDRD5 | Tyrphostin AG 1478 | 5 |
| iGMDRD103 | SN-38 | 2 |
| iGMDRD202 | Curcumin | 2 |
| iGMDRD137 | Indisulam | 3 |
| iGMDRD901 | ELCPK | 1 |
| iGMDRD123 | Isoevodiamine | 10 |
| iGMDRD698 | Neratinib | 3 |
| iGMDRD351 | GW843682X | 5 |
| iGMDRD237 | ABT-751 | 4 |
| iGMDRD583 | LDN 193189 | 2 |
| iGMDRD116 | CD437 | 8 |
| iGMDRD424 | Tamatinib | 3 |
| iGMDRD345 | Compound 10b [PMID: 11504634] | 4 |
| iGMDRD512 | nutlin 3 | 1 |
| iGMDRD356 | PNU-74654 | 2 |
| iGMDRD524 | ISX-9 | 6 |
| iGMDRD60 | Quinoclamine | 2 |
| iGMDRD369 | TGX-115 | 2 |
| iGMDRD64 | Parbendazole | 4 |
| iGMDRD506 | Fedratinib | 2 |
| iGMDRD562 | Navitoclax | 3 |
| iGMDRD398 | Sepantronium | 2 |
| iGMDRD100 | Zebularine | 2 |
| iGMDRD188 | Piperlongumine | 3 |
| iGMDRD887 | Compound 23 citrate | 3 |
| iGMDRD885 | Compound 110 | 5 |
| iGMDRD52 | Rotenone | 3 |
| iGMDRD870 | BRD63610 | 1 |
| iGMDRD802 | 4-methylfasudil | 1 |
| iGMDRD513 | BML-259 | 3 |
| iGMDRD138 | PX 12 | 2 |
| iGMDRD359 | OSW-1 | 2 |
| iGMDRD394 | BX-795 | 5 |
| iGMDRD61 | Kinetin riboside | 3 |
| iGMDRD193 | Fqi1 | 6 |
| iGMDRD446 | LY 2183240 | 4 |
| iGMDRD201 | SKI II | 1 |
| iGMDRD483 | SCH-529074 | 5 |
| iGMDRD781 | Sirolimus | 3 |
| iGMDRD670 | ML 210 | 1 |
| iGMDRD144 | NSC95397 | 3 |
| iGMDRD427 | ABT737 | 5 |
| iGMDRD387 | CHIR-99021 | 2 |
| iGMDRD420 | Leucascandrolide A | 5 |
| iGMDRD1008 | SR-II-138A | 5 |
| iGMDRD126 | Tipifarnib | 2 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in LRGUK
CLASSFICATION
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