CDK19

Summary: This gene encodes a protein that is one of the components of the Mediator co-activator complex. The Mediator complex is a multi-protein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. The protein encoded by this gene is similar to cyclin-dependent kinase 8 which can also be a component of the Mediator complex. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014].

Loading, please wait...
Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Namecyclin dependent kinase 19
OMIM IDMIM:614720
Ensembl IDEnsembl:ENSG00000155111
HGNC IDHGNC:HGNC:19338
PHARMGKB IDPA165617767
Map Location6q21

GO terms in CDK19


Loading, please wait...
Term Type
Evidence Type
GO Term ID
GO Des.
CC IBA GO:0005634 nucleus
CC IBA GO:0005829 cytosol
CC IBA GO:0016592 mediator complex
BP IBA GO:0006468 protein phosphorylation
BP IBA GO:0007346 regulation of mitotic cell cycle
BP IEA GO:0043065 positive regulation of apoptotic process
Showing 1 to 6 of 11 rows rows per page

Gene expression in normal tissue: CDK19

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

undefined22DNA replication2Stilbenoid, diarylheptanoid and gingerol biosynthesis1p53 pathway1Chromatin histone acetylation1Apoptosis regulation1Cell cycle1WNT signaling1Protein stability and degradation1

Pathways in CDK19


Loading, please wait...
Database
Pathway ID
Pathway Des.
reactome R-HSA-1266738 Developmental Biology
reactome R-HSA-1266738 Developmental Biology
reactome R-HSA-1430728 Metabolism
reactome R-HSA-1989781 PPARA activates gene expression
reactome R-HSA-381340 Transcriptional regulation of white adipocyte differentiation
reactome R-HSA-381340 Transcriptional regulation of white adipocyte differentiation
Showing 1 to 6 of 8 rows

Gene-Drug: Aster Plot


Loading, please wait...
Drug ID
Drug Name
Model Num.
iGMDRD57 Chloropentafluorobenzene 6
iGMDRD351 GW843682X 3
iGMDRD193 Fqi1 1
iGMDRD85 Ursolic acid 3
Showing 1 to 4 of 31 rows rows per page

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in CDK19

Loading, please wait...
Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

​​​​

SITE
DATATYPES
CLASSFICATION
Map

Copyright © 2018 Modellab | All Rights Reserved

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.