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iGMDRD701

Canonical SMILES: CCNC(=O)C1=C(C(=C2C=C(C(=CC2=O)O)C(C)C)ON1)C3=CC=C(C=C3)CN4CCOCC4

InChI: InChI=1S/C26H31N3O5/c1-4-27-26(32)24-23(18-7-5-17(6-8-18)15-29-9-11-33-12-10-29)25(34-28-24)20-13-19(16(2)3)21(30)14-22(20)31/h5-8,13-14,16,28,30H,4,9-12,15H2,1-3H3,(H,27,32)

InChI Key: SWDZPNJZKUGIIH-UHFFFAOYSA-N

Standard Name	CHEMBL	Pubchem CID	Drug Status	Drug Type
NVP-AUY922	CHEMBL3137334 CHEMBL252164	53401200	Alone	Small Molecule

Drug Pathways:

Protein stability and degradation

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot

Gene ID	Gene Name	Model Num.
6664	SOX11	3
471	ATIC	3
1464	CSPG4	3
10641	NPRL2	6
8444	DYRK3	3
132	ADK	2
2986	GUCY2F	2
57679	ALS2	3
5295	PIK3R1	1
23097	CDK19	3
83942	TSSK1B	2
6597	SMARCA4	1
81035	COLEC12	3
5133	PDCD1	5
7942	TFEB	2
51684	SUFU	2
6598	SMARCB1	5
1607	DGKB	2
1272	CNTN1	3
7253	TSHR	3
23310	NCAPD3	3
22821	RASA3	1
1545	CYP1B1	3
577	ADGRB3	1
8106	PABPN1	3
55023	PHIP	3
2313	FLI1	3
5579	PRKCB	1
5074	PAWR	3
11122	PTPRT	2
6722	SRF	2
10215	OLIG2	3
5465	PPARA	3
5314	PKHD1	3
55294	FBXW7	1
9578	CDC42BPB	1
23522	KAT6B	1
3227	HOXC11	3
6390	SDHB	6
54477	PLEKHA5	4
4610	MYCL	3
9693	RAPGEF2	4
2042	EPHA3	6
23255	MTCL1	2
80129	CCDC170	6
2736	GLI2	2
51804	SIX4	5
6928	HNF1B	1
83931	STK40	2
5898	RALA	3
3916	LAMP1	3
79971	WLS	3
29775	CARD10	3
783	CACNB2	1
6416	MAP2K4	2
50488	MINK1	2
8859	STK19	1
5568	PRKACG	4
7166	TPH1	6
9472	AKAP6	1
53942	CNTN5	1
1123	CHN1	2
1496	CTNNA2	3
7010	TEK	2
5450	POU2AF1	1
2272	FHIT	4
2066	ERBB4	2
7184	HSP90B1	2
10062	NR1H3	2
9794	MAML1	2
3236	HOXD10	3
7157	TP53	1
4088	SMAD3	2
27086	FOXP1	7
57194	ATP10A	2
4857	NOVA1	3
6184	RPN1	3
9639	ARHGEF10	5
1019	CDK4	1
7409	VAV1	2
11213	IRAK3	3
9967	THRAP3	2
105	ADARB2	2
4869	NPM1	2
1555	CYP2B6	2
55034	MOCOS	3
23043	TNIK	3
55437	STRADB	2
369	ARAF	1
5077	PAX3	4
4026	LPP	5
8997	KALRN	1
57551	TAOK1	2
6280	S100A9	3
170692	ADAMTS18	2
6654	SOS1	3
23373	CRTC1	3
285220	EPHA6	2
5606	MAP2K3	3
57144	PAK5	3
4214	MAP3K1	2
3702	ITK	2
9972	NUP153	2
3239	HOXD13	3
6046	BRD2	6
1000	CDH2	2
4145	MATK	3
7043	TGFB3	3
64919	BCL11B	2
640	BLK	2
5789	PTPRD	1
10461	MERTK	2
5156	PDGFRA	2
375056	MIA3	3
1544	CYP1A2	3
91754	NEK9	3
673	BRAF	2
4790	NFKB1	3
3315	HSPB1	3
23532	PRAME	1
83452	RAB33B	2
5598	MAPK7	4
8924	HERC2	3
2078	ERG	3
867	CBL	7
6095	RORA	4
146057	TTBK2	3
7468	NSD2	3
8178	ELL	3
5294	PIK3CG	3
7849	PAX8	3
9451	EIF2AK3	2
10010	TANK	1
5595	MAPK3	2
1869	E2F1	3
115701	ALPK2	2
6146	RPL22	2
23332	CLASP1	3
7059	THBS3	4
7036	TFR2	3
85415	RHPN2	2
8028	MLLT10	3
8648	NCOA1	3
2046	EPHA8	2
10595	ERN2	2
4619	MYH1	3
2869	GRK5	2
2317	FLNB	2
9021	SOCS3	1
8031	NCOA4	3
100124696	TEC	2
54101	RIPK4	3
283455	KSR2	2
5587	PRKD1	6
3717	JAK2	3
7099	TLR4	3
80216	ALPK1	1
5915	RARB	1
7112	TMPO	3
5087	PBX1	1
5324	PLAG1	6
3691	ITGB4	3
2534	FYN	2
4915	NTRK2	3
11086	ADAM29	2
2073	ERCC5	3
581	BAX	3
4763	NF1	2
57697	FANCM	2
494551	WEE2	3
2044	EPHA5	5
4629	MYH11	3
23683	PRKD3	3
2444	FRK	2
2892	GRIA3	6
1436	CSF1R	6

Gene in drug-gene network: Network Plot

Models in NVP-AUY922

SITE

DATATYPES

CLASSFICATION

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