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TSSK1B

Summary: TSSK1 belongs to a family of serine/threonine kinases highly expressed in testis (Hao et al., 2004 [PubMed 15044604]).[supplied by OMIM, Mar 2008].

Name	OMIM ID	Ensembl ID	HGNC ID	PHARMGKB ID	Map Location
testis specific serine kinase 1B	MIM:610709	Ensembl:ENSG00000212122	HGNC:HGNC:14968	PA37944	5q22.2

Gene Categories:

DRUGGABLE GENOME SERINE THREONINE KINASE KINASE

GO terms in TSSK1B

Term Type	Evidence Type	GO Term ID	GO Des.
CC	IEA	GO:0001669	acrosomal vesicle
CC	IBA	GO:0005634	nucleus
CC	IBA	GO:0005737	cytoplasm
CC	ISS	GO:0031514	motile cilium
BP	IBA	GO:0006468	protein phosphorylation
BP	IDA	GO:0006468	protein phosphorylation
BP	IEA	GO:0007275	multicellular organism development
BP	ISS	GO:0007286	spermatid development
BP	IBA	GO:0035556	intracellular signal transduction
MF	IDA	GO:0000287	magnesium ion binding
MF	IBA	GO:0004674	protein serine/threonine kinase activity
MF	IDA	GO:0004674	protein serine/threonine kinase activity
MF	IPI	GO:0005515	protein binding
MF	IDA	GO:0005524	ATP binding

Gene expression in normal tissue: TSSK1B

Select Project:

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in TSSK1B

Database	Pathway ID	Pathway Des.

Gene-Drug: Aster Plot

Drug ID	Drug Name	Model Num.
iGMDRD398	Sepantronium	2
iGMDRD329	Merck60	4
iGMDRD399	Selumetinib	2
iGMDRD5	Tyrphostin AG 1478	2
iGMDRD158	NSC141540	1
iGMDRD121	GMX1778	2
iGMDRD202	Curcumin	2
iGMDRD103	SN-38	3
iGMDRD639	YK 4-279	1
iGMDRD351	GW843682X	4
iGMDRD446	LY 2183240	3
iGMDRD280	CYTOCHALASIN B	3
iGMDRD177	Teniposide	2
iGMDRD123	Isoevodiamine	3
iGMDRD512	nutlin 3	3
iGMDRD387	CHIR-99021	2
iGMDRD701	NVP-AUY922	2

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in TSSK1B

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DATATYPES

CLASSFICATION

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.