TFEB


Summary:

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
OMIM IDMIM:600744
PHARMGKB IDPA36468
Map Location6p21.1

GO terms in TFEB


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Term Type
Evidence Type
GO Term ID
GO Des.
MF ISA GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding
MF ISM GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding
MF NAS GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding
MF IDA GO:0003700 DNA-binding transcription factor activity
MF NAS GO:0003700 DNA-binding transcription factor activity
MF IDA GO:0044212 transcription regulatory region DNA binding
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Gene expression in normal tissue: TFEB

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

undefined12Protein stability and degradation1Cell cycle1Apoptosis regulation1DNA replication1PI3K/MTOR signaling1Chromatin histone acetylation1Metabolism1

Pathways in TFEB


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Database
Pathway ID
Pathway Des.
kegg hsa04137 Mitophagy - animal - Homo sapiens (human)
wikipathways WP3844 PI3K-AKT-mTOR signaling pathway and therapeutic opportunities
wikipathways WP4241 Type 2 papillary renal cell carcinoma
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD289 Parthenolide 3
iGMDRD481 Dactolisib 3
iGMDRD121 GMX1778 3
iGMDRD474 Avrainvillamide 2
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in TFEB

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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