NPRL2

Summary:

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
NameNPR2 like, GATOR1 complex subunit
OMIM IDMIM:607072
Ensembl IDEnsembl:ENSG00000114388
HGNC IDHGNC:HGNC:24969
PHARMGKB IDPA165697981
Map Location3p21.31

Gene Categories:

KINASE

GO terms in NPRL2


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Term Type
Evidence Type
GO Term ID
GO Des.
BP IEA GO:0006468 protein phosphorylation
BP IBA GO:0006995 cellular response to nitrogen starvation
BP IBA GO:0010508 positive regulation of autophagy
BP IBA GO:0032007 negative regulation of TOR signaling
BP IMP GO:0032007 negative regulation of TOR signaling
BP IDA GO:0033673 negative regulation of kinase activity
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Gene expression in normal tissue: NPRL2

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

undefined32DNA replication2ERK MAPK signaling1p53 pathway1Apoptosis regulation1Cell cycle1Chromatin histone acetylation1Protein stability and degradation1Ferroptosis1

Pathways in NPRL2


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Database
Pathway ID
Pathway Des.
kegg hsa04150 mTOR signaling pathway - Homo sapiens (human)
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD158 NSC141540 6
iGMDRD103 SN-38 3
iGMDRD105 Triptolide 1
iGMDRD705 Nakiterpiosin 3
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in NPRL2

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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