GO terms in TAOK1


Term TypeEvidence TypeGO Term IDGO Des.
CCIBAGO:0005634nucleus
CCIBAGO:0005737cytoplasm
CCTASGO:0005829cytosol
CCIMPGO:0015630microtubule cytoskeleton
CCIMPGO:0048471perinuclear region of cytoplasm
CCHDAGO:0070062extracellular exosome
BPIBAGO:0000186activation of MAPKK activity
BPIEAGO:0000186activation of MAPKK activity
BPTASGO:0000187activation of MAPK activity
BPIMPGO:0000226microtubule cytoskeleton organization
BPIEAGO:0006281DNA repair
BPNASGO:0006468protein phosphorylation
BPIDAGO:0006974cellular response to DNA damage stimulus
BPIMPGO:0007026negative regulation of microtubule depolymerization
BPIMPGO:0007095mitotic G2 DNA damage checkpoint
BPTASGO:0007257activation of JUN kinase activity
BPIBAGO:0007346regulation of mitotic cell cycle
BPIBAGO:0023014signal transduction by protein phosphorylation
BPIBAGO:0032147activation of protein kinase activity
BPIMPGO:0032874positive regulation of stress-activated MAPK cascade
BPISSGO:0032956regulation of actin cytoskeleton organization
BPIDAGO:0046330positive regulation of JNK cascade
BPISSGO:0046777protein autophosphorylation
BPISSGO:0051493regulation of cytoskeleton organization
BPIMPGO:0070050neuron cellular homeostasis
BPISSGO:0070507regulation of microtubule cytoskeleton organization
BPIBAGO:0097194execution phase of apoptosis
BPIDAGO:0097194execution phase of apoptosis
BPIMPGO:1901985positive regulation of protein acetylation
MFISSGO:0004672protein kinase activity
MFNASGO:0004672protein kinase activity
MFIBAGO:0004674protein serine/threonine kinase activity
MFISSGO:0004674protein serine/threonine kinase activity
MFNASGO:0004674protein serine/threonine kinase activity
MFIBAGO:0004709MAP kinase kinase kinase activity
MFIPIGO:0005515protein binding
MFNASGO:0005524ATP binding
MFIDAGO:0016301kinase activity
MFNASGO:0016301kinase activity
MFNASGO:0016740transferase activity
MFIDAGO:0043014alpha-tubulin binding
MFISSGO:0043539protein serine/threonine kinase activator activity
MFIDAGO:0048487beta-tubulin binding

Gene expression in normal tissue: TAOK1

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in TAOK1


DatabasePathway IDPathway Des.
wikipathwaysWP2038Regulation of Microtubule Cytoskeleton
wikipathwaysWP382MAPK Signaling Pathway
pidp38_mkk3_6pathwayp38 MAPK signaling pathway
kegghsa04010MAPK signaling pathway - Homo sapiens (human)
reactomeR-HSA-141424Amplification of signal from the kinetochores
reactomeR-HSA-141444Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
reactomeR-HSA-162582Signal Transduction
reactomeR-HSA-1640170Cell Cycle
reactomeR-HSA-194315Signaling by Rho GTPases
reactomeR-HSA-195258RHO GTPase Effectors
reactomeR-HSA-2467813Separation of Sister Chromatids
reactomeR-HSA-2500257Resolution of Sister Chromatid Cohesion
reactomeR-HSA-2555396Mitotic Metaphase and Anaphase
reactomeR-HSA-5663220RHO GTPases Activate Formins
reactomeR-HSA-68877Mitotic Prometaphase
reactomeR-HSA-68882Mitotic Anaphase
reactomeR-HSA-68886M Phase
reactomeR-HSA-69278Cell Cycle, Mitotic
reactomeR-HSA-69618Mitotic Spindle Checkpoint
reactomeR-HSA-69620Cell Cycle Checkpoints

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD481Dactolisib2
iGMDRD77Itraconazole2
iGMDRD705Nakiterpiosin6
iGMDRD434BMS-5369242
iGMDRD5Tyrphostin AG 14782
iGMDRD103SN-383
iGMDRD138PX 122
iGMDRD202Curcumin2
iGMDRD300Tozasertib1
iGMDRD191FMK1
iGMDRD147Prima-11
iGMDRD398Sepantronium5
iGMDRD780PP-302
iGMDRD871BRD63682
iGMDRD872BRD71371
iGMDRD483SCH-5290741
iGMDRD701NVP-AUY9222
iGMDRD512nutlin 31
iGMDRD387CHIR-990213
iGMDRD772BRD47702
iGMDRD126Tipifarnib4
iGMDRD511CHEMBL3993793
iGMDRD123Isoevodiamine3
iGMDRD679Bistramide A2
iGMDRD280CYTOCHALASIN B8
iGMDRD57Chloropentafluorobenzene2
iGMDRD351GW843682X2
iGMDRD341Triacsin c2

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in TAOK1

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