SOX11
Summary: This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may function in the developing nervous system and play a role in tumorigenesis. [provided by RefSeq, Jul 2008].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
NameSRY-box 11 OMIM IDMIM:600898 Ensembl IDEnsembl:ENSG00000176887 HGNC IDHGNC:HGNC:11191 PHARMGKB IDPA36028 Map Location2p25.2 | |||||
Gene Categories:
TUMOR SUPPRESSORGO terms in SOX11
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IBA | GO:0000122 | negative regulation of transcription by RNA polymerase II |
| BP | IDA | GO:0000122 | negative regulation of transcription by RNA polymerase II |
| BP | ISS | GO:0001501 | skeletal system development |
| BP | IBA | GO:0001654 | eye development |
| BP | IEA | GO:0001822 | kidney development |
| BP | ISS | GO:0001841 | neural tube formation |
Gene expression in normal tissue: SOX11
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in SOX11
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| wikipathways | WP3527 | Preimplantation Embryo |
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Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in SOX11
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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