iGMDRD219


Canonical SMILES: C1CN(CCN1)CC(CN2C3=C(C=C(C=C3)Br)C4=C2C=CC(=C4)Br)O

InChI: InChI=1S/C19H21Br2N3O/c20-13-1-3-18-16(9-13)17-10-14(21)2-4-19(17)24(18)12-15(25)11-23-7-5-22-6-8-23/h1-4,9-10,15,22,25H,5-8,11-12H2

InChI Key: KUUJEXLRLIPQQJ-UHFFFAOYSA-N

Standard NamePubchem CIDDrug StatusDrug Type
Bax channel blocker2729030ClassificationSmall Molecule

Drug Targets:

BAX

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


Gene IDGene NameModel Num.
1147CHUK3
6664SOX113
7837PXDN2
132ADK3
6774STAT32
4168MCF22
2956MSH63
4303FOXO41
57679ALS23
8289ARID1A2
6351CCL42
51231VRK31
2335FN13
84700MYO18B2
81035COLEC123
9530BAG42
7253TSHR3
7080NKX2-19
1387CREBBP2
2313FLI13
5579PRKCB3
11200CHEK22
10178TENM14
8558CDK103
5074PAWR3
2977GUCY1A23
23617TSSK23
5899RALB2
974CD79B3
8784TNFRSF181
23522KAT6B5
2115ETV11
5081PAX73
5607MAP2K52
2268FGR3
222484LNX21
1586CYP17A12
3556IL1RAP3
4300MLLT35
6041RNASEL1
7016TESK13
22858ICK3
2064ERBB23
9759HDAC42
6098ROS12
9472AKAP63
5229PGGT1B3
139285AMER12
5450POU2AF11
898CCNE12
2272FHIT6
27347STK391
6092ROBO23
79058ASPSCR13
6794STK114
93210PGAP31
1019CDK43
9088PKMYT13
57591MRTFA1
7495XBP1P11
652BMP43
8997KALRN2
23469PHF32
6654SOS12
4139MARK13
10733PLK43
5727PTCH15
285220EPHA63
10926DBF47
4958OMD3
9972NUP1533
3239HOXD133
84823LMNB23
10565ARFGEF13
744MPPED22
1956EGFR1
8445DYRK22
8900CCNA12
10971YWHAQ3
1544CYP1A23
6095RORA6
9451EIF2AK33
4791NFKB26
23049SMG13
51592TRIM333
4914NTRK13
115701ALPK22
4004LMO13
1445CSK2
6789STK43
7454WAS2
7036TFR23
29941PKN33
282974STK32C3
344905ATP13A52
4297KMT2A7
5291PIK3CB2
3985LIMK23
9201DCLK13
2049EPHB33
283455KSR23
4628MYH105
6778STAT63
23301EHBP12
51562MBIP8
3516RBPJ3
5915RARB1
444ASPH4
7046TGFBR12
54790TET23
5288PIK3C2G3
5287PIK3C2B2
3679ITGA72

Gene in drug-gene network: Network Plot

Models in Bax channel blocker

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