TENM1


Summary: The protein encoded by this gene belongs to the tenascin family and teneurin subfamily. It is expressed in the neurons and may function as a cellular signal transducer. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
teneurin transmembrane protein 1MIM:300588Ensembl:ENSG00000009694HGNC:HGNC:8117PA31904Xq25

GO terms in TENM1


Term TypeEvidence TypeGO Term IDGO Des.
CCTASGO:0005576extracellular region
CCISSGO:0005634nucleus
CCISSGO:0005737cytoplasm
CCISSGO:0005783endoplasmic reticulum
CCISSGO:0005794Golgi apparatus
CCISSGO:0005856cytoskeleton
CCISSGO:0005886plasma membrane
CCISSGO:0005887integral component of plasma membrane
CCISSGO:0016363nuclear matrix
CCISSGO:0016607nuclear speck
CCIBAGO:0043005neuron projection
CCISSGO:0048471perinuclear region of cytoplasm
BPIEAGO:0006351transcription, DNA-templated
BPISSGO:0006359regulation of transcription by RNA polymerase III
BPTASGO:0006955immune response
BPIBAGO:0007157heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
BPIEAGO:0007218neuropeptide signaling pathway
BPTASGO:0007399nervous system development
BPTASGO:0008285negative regulation of cell proliferation
BPISSGO:0030838positive regulation of actin filament polymerization
BPISSGO:0033138positive regulation of peptidyl-serine phosphorylation
BPISSGO:0043406positive regulation of MAP kinase activity
BPIBAGO:0048666neuron development
BPISSGO:0051491positive regulation of filopodium assembly
BPISSGO:0090316positive regulation of intracellular protein transport
MFTASGO:0008201heparin binding
MFIBAGO:0042803protein homodimerization activity
MFISSGO:0042803protein homodimerization activity
MFIBAGO:0046982protein heterodimerization activity
MFISSGO:0046982protein heterodimerization activity
MFIBAGO:0050839cell adhesion molecule binding

Gene expression in normal tissue: TENM1

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in TENM1


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD322FK 8662
iGMDRD300Tozasertib4
iGMDRD886Compound 1541A2
iGMDRD505Pevonedistat8
iGMDRD246NPC262
iGMDRD662JQ-14
iGMDRD286Nsc 6328391
iGMDRD871BRD63685
iGMDRD872BRD71372
iGMDRD481Dactolisib1
iGMDRD267Oligomycin A7
iGMDRD105Triptolide1
iGMDRD705Nakiterpiosin3
iGMDRD434BMS-5369243
iGMDRD202Curcumin1
iGMDRD121GMX17781
iGMDRD137Indisulam2
iGMDRD435BI-25363
iGMDRD698Neratinib2
iGMDRD219Bax channel blocker4
iGMDRD341Triacsin c4
iGMDRD85Ursolic acid2
iGMDRD523Cyanoquinoline, 112
iGMDRD532Olaparib2
iGMDRD150RITA2
iGMDRD424Tamatinib1
iGMDRD512nutlin 34
iGMDRD23Gossypol8
iGMDRD64Parbendazole1
iGMDRD506Fedratinib5
iGMDRD100Zebularine2
iGMDRD887Compound 23 citrate7
iGMDRD318PAC-13
iGMDRD30917AAG1
iGMDRD52Rotenone2
iGMDRD260FQI-21
iGMDRD297Austocystin D5
iGMDRD679Bistramide A1
iGMDRD280CYTOCHALASIN B1
iGMDRD152179324-69-75
iGMDRD446LY 21832403
iGMDRD494Neopeltolide2
iGMDRD144NSC953971
iGMDRD546BMS-7548074
iGMDRD427ABT7375
iGMDRD420Leucascandrolide A2
iGMDRD772BRD47702
iGMDRD151CHM-18

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in TENM1

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