OMD
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| osteomodulin | Ensembl:ENSG00000127083 | HGNC:HGNC:8134 | PA31921 | 9q22.31 |
Gene Categories:
DRUGGABLE GENOMEGO terms in OMD
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | TAS | GO:0005576 | extracellular region |
| CC | TAS | GO:0005796 | Golgi lumen |
| CC | TAS | GO:0043202 | lysosomal lumen |
| CC | IEA | GO:0062023 | collagen-containing extracellular matrix |
| CC | HDA | GO:0070062 | extracellular exosome |
| BP | IEA | GO:0007155 | cell adhesion |
| BP | TAS | GO:0018146 | keratan sulfate biosynthetic process |
| BP | IEA | GO:0030500 | regulation of bone mineralization |
| BP | TAS | GO:0042340 | keratan sulfate catabolic process |
Gene expression in normal tissue: OMD
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in OMD
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-1430728 | Metabolism |
| reactome | R-HSA-1630316 | Glycosaminoglycan metabolism |
| reactome | R-HSA-1638074 | Keratan sulfate/keratin metabolism |
| reactome | R-HSA-1643685 | Disease |
| reactome | R-HSA-2022854 | Keratan sulfate biosynthesis |
| reactome | R-HSA-2022857 | Keratan sulfate degradation |
| reactome | R-HSA-3560782 | Diseases associated with glycosaminoglycan metabolism |
| reactome | R-HSA-3656225 | Defective CHST6 causes MCDC1 |
| reactome | R-HSA-3656243 | Defective ST3GAL3 causes MCT12 and EIEE15 |
| reactome | R-HSA-3656244 | Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) |
| reactome | R-HSA-3781865 | Diseases of glycosylation |
| reactome | R-HSA-71387 | Metabolism of carbohydrates |
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD634 | SCHEMBL2608041 | 3 |
| iGMDRD297 | Austocystin D | 3 |
| iGMDRD886 | Compound 1541A | 3 |
| iGMDRD60 | Quinoclamine | 3 |
| iGMDRD280 | CYTOCHALASIN B | 4 |
| iGMDRD506 | Fedratinib | 3 |
| iGMDRD662 | JQ-1 | 3 |
| iGMDRD219 | Bax channel blocker | 3 |
| iGMDRD871 | BRD6368 | 3 |
| iGMDRD887 | Compound 23 citrate | 3 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in OMD
CLASSFICATION
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Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.