MBIP
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| MAP3K12 binding inhibitory protein 1 | MIM:609431 | Ensembl:ENSG00000151332 | HGNC:HGNC:20427 | PA134929415 | 14q13.3 |
GO terms in MBIP
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | TAS | GO:0000173 | inactivation of MAPK activity involved in osmosensory signaling pathway |
| BP | IBA | GO:0032324 | molybdopterin cofactor biosynthetic process |
| BP | IDA | GO:0043966 | histone H3 acetylation |
| CC | IDA | GO:0005634 | nucleus |
| CC | IDA | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex |
| CC | IDA | GO:0005730 | nucleolus |
| CC | IBA | GO:0005829 | cytosol |
| CC | IDA | GO:0005829 | cytosol |
| MF | TAS | GO:0004860 | protein kinase inhibitor activity |
| MF | IPI | GO:0005515 | protein binding |
| MF | IBA | GO:0030366 | molybdopterin synthase activity |
| MF | IPI | GO:0042802 | identical protein binding |
Gene expression in normal tissue: MBIP
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in MBIP
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-3214847 | HATs acetylate histones |
| reactome | R-HSA-3247509 | Chromatin modifying enzymes |
| reactome | R-HSA-4839726 | Chromatin organization |
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD289 | Parthenolide | 3 |
| iGMDRD782 | DC-45-A2 | 3 |
| iGMDRD474 | Avrainvillamide | 3 |
| iGMDRD138 | PX 12 | 1 |
| iGMDRD121 | GMX1778 | 5 |
| iGMDRD23 | Gossypol | 6 |
| iGMDRD42 | Vorinostat | 2 |
| iGMDRD322 | FK 866 | 9 |
| iGMDRD300 | Tozasertib | 7 |
| iGMDRD505 | Pevonedistat | 2 |
| iGMDRD886 | Compound 1541A | 10 |
| iGMDRD60 | Quinoclamine | 7 |
| iGMDRD662 | JQ-1 | 2 |
| iGMDRD398 | Sepantronium | 3 |
| iGMDRD188 | Piperlongumine | 2 |
| iGMDRD414 | MST-312 | 1 |
| iGMDRD887 | Compound 23 citrate | 5 |
| iGMDRD523 | Cyanoquinoline, 11 | 2 |
| iGMDRD79 | Gemcitabine | 3 |
| iGMDRD150 | RITA | 2 |
| iGMDRD126 | Tipifarnib | 2 |
| iGMDRD375 | GW-405833 | 3 |
| iGMDRD435 | BI-2536 | 5 |
| iGMDRD132 | (-)-gallocatechin-3-O-gallate | 3 |
| iGMDRD883 | CIL55A | 10 |
| iGMDRD297 | Austocystin D | 2 |
| iGMDRD351 | GW843682X | 2 |
| iGMDRD57 | Chloropentafluorobenzene | 1 |
| iGMDRD219 | Bax channel blocker | 8 |
| iGMDRD152 | 179324-69-7 | 3 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in MBIP
CLASSFICATION
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