RALB
Summary: This gene encodes a GTP-binding protein that belongs to the small GTPase superfamily and Ras family of proteins. GTP-binding proteins mediate the transmembrane signaling initiated by the occupancy of certain cell surface receptors. [provided by RefSeq, Jul 2008].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:179551 Ensembl IDEnsembl:ENSG00000144118 HGNC IDHGNC:HGNC:9840 PHARMGKB IDPA34198 Map Location2q14.2 | |||||
GO terms in RALB
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IDA | GO:0003924 | GTPase activity |
| MF | IPI | GO:0005515 | protein binding |
| MF | IDA | GO:0005525 | GTP binding |
| MF | IMP | GO:0005525 | GTP binding |
| MF | IDA | GO:0019003 | GDP binding |
| MF | IPI | GO:0031625 | ubiquitin protein ligase binding |
Gene expression in normal tissue: RALB
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in RALB
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-162582 | Signal Transduction |
| reactome | R-HSA-166520 | Signaling by NTRKs |
| reactome | R-HSA-167044 | Signalling to RAS |
| reactome | R-HSA-171007 | p38MAPK events |
| reactome | R-HSA-187037 | Signaling by NTRK1 (TRKA) |
| reactome | R-HSA-187687 | Signalling to ERKs |
Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in RALB
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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