CDK10


Summary: The protein encoded by this gene belongs to the CDK subfamily of the Ser/Thr protein kinase family. The CDK subfamily members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and are known to be essential for cell cycle progression. This kinase has been shown to play a role in cellular proliferation and its function is limited to cell cycle G2-M phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009].

Loading, please wait...
Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
OMIM IDMIM:603464
PHARMGKB IDPA26307
Map Location16q24.3

GO terms in CDK10


Loading, please wait...
Term Type
Evidence Type
GO Term ID
GO Des.
CC IBA GO:0005634 nucleus
CC IEA GO:0005737 cytoplasm
CC IDA GO:0036064 ciliary basal body
BP IBA GO:0006468 protein phosphorylation
BP TAS GO:0007089 traversing start control point of mitotic cell cycle
BP TAS GO:0008285 negative regulation of cell proliferation
Showing 1 to 6 of 15 rows rows per page

Gene expression in normal tissue: CDK10

Gene-model tissue-cancer distribution: Bubble Plot

BOWEtissue: BOWE cancer: BOWEL model num: 0BOWELtissue: BOWEL cancer: undefined model num: 5undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 24

Gene-drug pathway distribution

undefined7Chromatin histone acetylation1Apoptosis regulation1

Pathways in CDK10


Loading, please wait...
Database
Pathway ID
Pathway Des.
No matching records found

Gene-Drug: Aster Plot


Loading, please wait...
Drug ID
Drug Name
Model Num.
iGMDRD318 PAC-1 4
iGMDRD289 Parthenolide 1
iGMDRD105 Triptolide 3
iGMDRD126 Tipifarnib 3
Showing 1 to 4 of 9 rows

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in CDK10

Loading, please wait...
Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

​​​​