TSSK2
Summary: TSSK2 belongs to a family of serine/threonine kinases highly expressed in testis (Hao et al., 2004 [PubMed 15044604]).[supplied by OMIM, Mar 2008].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| testis specific serine kinase 2 | MIM:610710 | Ensembl:ENSG00000206203 | HGNC:HGNC:11401 | PA36208 | 22q11.21 |
GO terms in TSSK2
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IDA | GO:0000287 | magnesium ion binding |
| MF | ISS | GO:0000287 | magnesium ion binding |
| MF | IBA | GO:0004674 | protein serine/threonine kinase activity |
| MF | IDA | GO:0004674 | protein serine/threonine kinase activity |
| MF | ISS | GO:0004674 | protein serine/threonine kinase activity |
| MF | IPI | GO:0005515 | protein binding |
| MF | ISS | GO:0005524 | ATP binding |
| CC | IEA | GO:0001669 | acrosomal vesicle |
| CC | HDA | GO:0005634 | nucleus |
| CC | IBA | GO:0005634 | nucleus |
| CC | IBA | GO:0005737 | cytoplasm |
| CC | ISS | GO:0005737 | cytoplasm |
| CC | IEA | GO:0005814 | centriole |
| BP | IBA | GO:0006468 | protein phosphorylation |
| BP | ISS | GO:0006468 | protein phosphorylation |
| BP | IEA | GO:0007275 | multicellular organism development |
| BP | ISS | GO:0007286 | spermatid development |
| BP | IBA | GO:0035556 | intracellular signal transduction |
| BP | IDA | GO:0046777 | protein autophosphorylation |
Gene expression in normal tissue: TSSK2
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in TSSK2
| Database | Pathway ID | Pathway Des. |
|---|
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD314 | Tanespimycin | 4 |
| iGMDRD351 | GW843682X | 2 |
| iGMDRD219 | Bax channel blocker | 3 |
| iGMDRD375 | GW-405833 | 2 |
| iGMDRD634 | SCHEMBL2608041 | 4 |
| iGMDRD945 | ML214 | 2 |
| iGMDRD883 | CIL55A | 1 |
| iGMDRD394 | BX-795 | 1 |
| iGMDRD177 | Teniposide | 6 |
| iGMDRD280 | CYTOCHALASIN B | 5 |
| iGMDRD512 | nutlin 3 | 5 |
| iGMDRD210 | AC55649 | 3 |
| iGMDRD494 | Neopeltolide | 5 |
| iGMDRD150 | RITA | 2 |
| iGMDRD345 | Compound 10b [PMID: 11504634] | 5 |
| iGMDRD329 | Merck60 | 3 |
| iGMDRD577 | BIX01294 | 4 |
| iGMDRD188 | Piperlongumine | 2 |
| iGMDRD872 | BRD7137 | 2 |
| iGMDRD300 | Tozasertib | 3 |
| iGMDRD103 | SN-38 | 2 |
| iGMDRD137 | Indisulam | 3 |
| iGMDRD158 | NSC141540 | 4 |
| iGMDRD885 | Compound 110 | 1 |
| iGMDRD415 | LE-135 | 2 |
| iGMDRD267 | Oligomycin A | 2 |
| iGMDRD187 | BRD9876 | 3 |
| iGMDRD289 | Parthenolide | 4 |
| iGMDRD434 | BMS-536924 | 1 |
| iGMDRD171 | Pemetrexed | 3 |
| iGMDRD782 | DC-45-A2 | 2 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in TSSK2
CLASSFICATION
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