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iGMDRD415

Canonical SMILES: CC1(CCC(C2=CC3=C(C=C21)N=C(C4=CC=CC=C4N3C)C5=CC=C(C=C5)C(=O)O)(C)C)C

InChI: InChI=1S/C29H30N2O2/c1-28(2)14-15-29(3,4)22-17-25-23(16-21(22)28)30-26(18-10-12-19(13-11-18)27(32)33)20-8-6-7-9-24(20)31(25)5/h6-13,16-17H,14-15H2,1-5H3,(H,32,33)

InChI Key: YZZAIQOVMHVWBS-UHFFFAOYSA-N

Standard Name	CHEMBL	Pubchem CID	Drug Status	Drug Type
LE-135	CHEMBL37708	10410900	Alone	Small Molecule

Drug Targets:

RARB

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot

Gene ID	Gene Name	Model Num.
331	XIAP	3
7514	XPO1	1
81037	CLPTM1L	3
11183	MAP4K5	1
3708	ITPR1	2
1520	CTSS	1
7272	TTK	1
4750	NEK1	3
55215	FANCI	3
9869	SETDB1	1
5079	PAX5	3
10863	ADAM28	3
1813	DRD2	3
2043	EPHA4	3
5788	PTPRC	3
31	ACACA	1
23617	TSSK2	2
5159	PDGFRB	1
7373	COL14A1	1
4361	MRE11	2
83439	TCF7L1	2
440279	UNC13C	3
5900	RALGDS	3
6256	RXRA	2
329	BIRC2	3
22806	IKZF3	3
8313	AXIN2	1
1050	CEBPA	1
10188	TNK2	2
4982	TNFRSF11B	2
7078	TIMP3	3
8395	PIP5K1B	2
1452	CSNK1A1	2
5924	RASGRF2	1
1496	CTNNA2	1
9794	MAML1	1
28514	DLL1	3
8218	CLTCL1	2
2329	FMO4	2
5650	KLK7	2
4437	MSH3	4
51284	TLR7	3
5290	PIK3CA	5
1000	CDH2	3
7075	TIE1	2
90956	ADCK2	3
1440	CSF3	3
6776	STAT5A	2
5156	PDGFRA	2
375056	MIA3	1
137872	ADHFE1	3
673	BRAF	4
3485	IGFBP2	1
8924	HERC2	2
11126	CD160	3
8626	TP63	1
4298	MLLT1	2
5979	RET	3
9321	TRIP11	2
654780	LOC654780	3
162968	ZNF497	3
57521	RPTOR	2
7030	TFE3	2
3554	IL1R1	3
140803	TRPM6	3
8301	PICALM	3
7465	WEE1	3
55356	SLC22A15	3
53904	MYO3A	3
22843	PPM1E	3
8394	PIP5K1A	2
2353	FOS	3
5291	PIK3CB	2
4619	MYH1	2
10111	RAD50	2
54101	RIPK4	3
6093	ROCK1	3
1719	DHFR	4
57007	ACKR3	3
8317	CDC7	2
80216	ALPK1	1
84072	HORMAD1	2
23250	ATP11A	3
2122	MECOM	1
2903	GRIN2A	2
63923	TNN	3
3691	ITGB4	2
7403	KDM6A	4
7508	XPC	2
112268437	LOC112268437	3

Gene in drug-gene network: Network Plot

Models in LE-135

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DATATYPES

CLASSFICATION

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