UNC13C


Summary:

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
unc-13 homolog CMIM:614568Ensembl:ENSG00000137766HGNC:HGNC:23149PA13487008715q21.3

GO terms in UNC13C


Term TypeEvidence TypeGO Term IDGO Des.
MFIEAGO:0005509calcium ion binding
MFIBAGO:0005516calmodulin binding
MFIEAGO:0005543phospholipid binding
MFIBAGO:0017075syntaxin-1 binding
MFIEAGO:0019992diacylglycerol binding
BPISSGO:0007268chemical synaptic transmission
BPIBAGO:0007528neuromuscular junction development
BPIBAGO:0016081synaptic vesicle docking
BPIBAGO:0016082synaptic vesicle priming
BPIBAGO:0016188synaptic vesicle maturation
BPIEAGO:0031914negative regulation of synaptic plasticity
BPIBAGO:0035249synaptic transmission, glutamatergic
BPIEAGO:0035556intracellular signal transduction
BPIBAGO:0061789dense core granule priming
BPIBAGO:0099525presynaptic dense core vesicle exocytosis
CCIEAGO:0005737cytoplasm
CCIBAGO:0005886plasma membrane
CCISSGO:0005886plasma membrane
CCIEAGO:0030054cell junction
CCIBAGO:0030672synaptic vesicle membrane
CCIBAGO:0031594neuromuscular junction
CCIBAGO:0042734presynaptic membrane
CCIEAGO:0042734presynaptic membrane
CCIBAGO:0043195terminal bouton
CCIEAGO:0044305calyx of Held
CCIBAGO:0048786presynaptic active zone
CCTASGO:0048786presynaptic active zone
CCIBAGO:0098831presynaptic active zone cytoplasmic component

Gene expression in normal tissue: UNC13C

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in UNC13C


DatabasePathway IDPathway Des.
kegghsa04721Synaptic vesicle cycle - Homo sapiens (human)
wikipathwaysWP2267Synaptic Vesicle Pathway

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD494Neopeltolide2
iGMDRD781Sirolimus4
iGMDRD427ABT7376
iGMDRD546BMS-7548072
iGMDRD670ML 2102
iGMDRD420Leucascandrolide A5
iGMDRD1008SR-II-138A5
iGMDRD772BRD47703
iGMDRD151CHM-13
iGMDRD554CHEMBL14341373
iGMDRD433Lexibulin2
iGMDRD718Pyrvinium pamoate4
iGMDRD639YK 4-2792
iGMDRD61Kinetin riboside3
iGMDRD193Fqi12
iGMDRD446LY 21832403
iGMDRD201SKI II5
iGMDRD318PAC-12
iGMDRD8012,4-dideoxy-DC-45-A22
iGMDRD782DC-45-A26
iGMDRD260FQI-23
iGMDRD138PX 124
iGMDRD524ISX-93
iGMDRD690PRIMA-1MET2
iGMDRD60Quinoclamine2
iGMDRD64Parbendazole3
iGMDRD577BIX012945
iGMDRD562Navitoclax4
iGMDRD188Piperlongumine2
iGMDRD399Selumetinib4
iGMDRD79Gemcitabine6
iGMDRD560MK-22063
iGMDRD116CD4372
iGMDRD532Olaparib3
iGMDRD512nutlin 33
iGMDRD84Lovastatin acid3
iGMDRD307Manumycin A5
iGMDRD123Isoevodiamine2
iGMDRD177Teniposide8
iGMDRD351GW843682X2
iGMDRD237ABT-7511
iGMDRD415LE-1353
iGMDRD267Oligomycin A2
iGMDRD231Importazole1
iGMDRD289Parthenolide2
iGMDRD105Triptolide1
iGMDRD705Nakiterpiosin2
iGMDRD434BMS-5369242
iGMDRD103SN-385
iGMDRD202Curcumin7
iGMDRD158NSC1415407
iGMDRD137Indisulam2
iGMDRD82Quiflapon3
iGMDRD505Pevonedistat5
iGMDRD246NPC265
iGMDRD329Merck604
iGMDRD414MST-3122
iGMDRD872BRD71372

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in UNC13C

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