MIA3


Summary:

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
MIA SH3 domain ER export factor 3MIM:613455Ensembl:ENSG00000154305HGNC:HGNC:24008PA1434855361q41

Gene Categories:

TRANSPORTER

GO terms in MIA3


Term TypeEvidence TypeGO Term IDGO Des.
MFIPIGO:0005515protein binding
MFIBAGO:0042954lipoprotein transporter activity
MFIMPGO:0042954lipoprotein transporter activity
CCIEAGO:0000139Golgi membrane
CCTASGO:0005788endoplasmic reticulum lumen
CCIBAGO:0005789endoplasmic reticulum membrane
CCIDAGO:0005789endoplasmic reticulum membrane
CCTASGO:0005789endoplasmic reticulum membrane
CCHDAGO:0016020membrane
CCIDAGO:0016021integral component of membrane
CCIDAGO:0043231intracellular membrane-bounded organelle
CCIBAGO:0070971endoplasmic reticulum exit site
CCIDAGO:0070971endoplasmic reticulum exit site
BPIDAGO:0002687positive regulation of leukocyte migration
BPIMPGO:0006887exocytosis
BPIBAGO:0006888ER to Golgi vesicle-mediated transport
BPIMPGO:0006888ER to Golgi vesicle-mediated transport
BPTASGO:0006888ER to Golgi vesicle-mediated transport
BPIDAGO:0007162negative regulation of cell adhesion
BPIBAGO:0009306protein secretion
BPIMPGO:0015031protein transport
BPIDAGO:0030336negative regulation of cell migration
BPIBAGO:0035459cargo loading into vesicle
BPIDAGO:0042060wound healing
BPIMPGO:0042953lipoprotein transport
BPTASGO:0043687post-translational protein modification
BPTASGO:0044267cellular protein metabolic process
BPIMPGO:0090110cargo loading into COPII-coated vesicle

Gene expression in normal tissue: MIA3

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in MIA3


DatabasePathway IDPathway Des.
reactomeR-HSA-199977ER to Golgi Anterograde Transport
reactomeR-HSA-199991Membrane Trafficking
reactomeR-HSA-381426Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
reactomeR-HSA-392499Metabolism of proteins
reactomeR-HSA-446203Asparagine N-linked glycosylation
reactomeR-HSA-5653656Vesicle-mediated transport
reactomeR-HSA-5694530Cargo concentration in the ER
reactomeR-HSA-597592Post-translational protein modification
reactomeR-HSA-8957275Post-translational protein phosphorylation
reactomeR-HSA-948021Transport to the Golgi and subsequent modification

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD705Nakiterpiosin3
iGMDRD434BMS-5369246
iGMDRD415LE-1351
iGMDRD213SMR0000686502
iGMDRD267Oligomycin A2
iGMDRD103SN-383
iGMDRD220fumonisin B13
iGMDRD121GMX17783
iGMDRD137Indisulam6
iGMDRD300Tozasertib2
iGMDRD147Prima-12
iGMDRD246NPC264
iGMDRD322FK 8662
iGMDRD414MST-3123
iGMDRD286Nsc 6328392
iGMDRD367Ro 28-16752
iGMDRD871BRD63683
iGMDRD872BRD71373
iGMDRD662JQ-13
iGMDRD424Tamatinib1
iGMDRD345Compound 10b [PMID: 11504634]3
iGMDRD701NVP-AUY9223
iGMDRD512nutlin 34
iGMDRD901ELCPK3
iGMDRD123Isoevodiamine3
iGMDRD945ML2141
iGMDRD351GW843682X3
iGMDRD237ABT-7513
iGMDRD782DC-45-A21
iGMDRD294Batimastat1
iGMDRD513BML-2593
iGMDRD270Ciclosporin2
iGMDRD247Blebbistatin3
iGMDRD260FQI-23
iGMDRD255SB2250022
iGMDRD8024-methylfasudil3
iGMDRD64Parbendazole2
iGMDRD23Gossypol2
iGMDRD524ISX-92
iGMDRD188Piperlongumine4
iGMDRD100Zebularine4
iGMDRD887Compound 23 citrate2
iGMDRD399Selumetinib2
iGMDRD74Idarubicin2
iGMDRD577BIX012942
iGMDRD398Sepantronium3
iGMDRD562Navitoclax6
iGMDRD427ABT7373
iGMDRD546BMS-7548072
iGMDRD781Sirolimus5
iGMDRD126Tipifarnib5
iGMDRD151CHM-13
iGMDRD1008SR-II-138A2
iGMDRD579PF7504
iGMDRD394BX-7953
iGMDRD466Chaetocin3
iGMDRD634SCHEMBL26080411
iGMDRD446LY 21832406
iGMDRD316N9-Isopropyl-olomoucine1
iGMDRD639YK 4-2791
iGMDRD193Fqi14
iGMDRD61Kinetin riboside3

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in MIA3

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