MIA3
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| MIA SH3 domain ER export factor 3 | MIM:613455 | Ensembl:ENSG00000154305 | HGNC:HGNC:24008 | PA143485536 | 1q41 |
Gene Categories:
TRANSPORTERGO terms in MIA3
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IPI | GO:0005515 | protein binding |
| MF | IBA | GO:0042954 | lipoprotein transporter activity |
| MF | IMP | GO:0042954 | lipoprotein transporter activity |
| CC | IEA | GO:0000139 | Golgi membrane |
| CC | TAS | GO:0005788 | endoplasmic reticulum lumen |
| CC | IBA | GO:0005789 | endoplasmic reticulum membrane |
| CC | IDA | GO:0005789 | endoplasmic reticulum membrane |
| CC | TAS | GO:0005789 | endoplasmic reticulum membrane |
| CC | HDA | GO:0016020 | membrane |
| CC | IDA | GO:0016021 | integral component of membrane |
| CC | IDA | GO:0043231 | intracellular membrane-bounded organelle |
| CC | IBA | GO:0070971 | endoplasmic reticulum exit site |
| CC | IDA | GO:0070971 | endoplasmic reticulum exit site |
| BP | IDA | GO:0002687 | positive regulation of leukocyte migration |
| BP | IMP | GO:0006887 | exocytosis |
| BP | IBA | GO:0006888 | ER to Golgi vesicle-mediated transport |
| BP | IMP | GO:0006888 | ER to Golgi vesicle-mediated transport |
| BP | TAS | GO:0006888 | ER to Golgi vesicle-mediated transport |
| BP | IDA | GO:0007162 | negative regulation of cell adhesion |
| BP | IBA | GO:0009306 | protein secretion |
| BP | IMP | GO:0015031 | protein transport |
| BP | IDA | GO:0030336 | negative regulation of cell migration |
| BP | IBA | GO:0035459 | cargo loading into vesicle |
| BP | IDA | GO:0042060 | wound healing |
| BP | IMP | GO:0042953 | lipoprotein transport |
| BP | TAS | GO:0043687 | post-translational protein modification |
| BP | TAS | GO:0044267 | cellular protein metabolic process |
| BP | IMP | GO:0090110 | cargo loading into COPII-coated vesicle |
Gene expression in normal tissue: MIA3
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in MIA3
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-199977 | ER to Golgi Anterograde Transport |
| reactome | R-HSA-199991 | Membrane Trafficking |
| reactome | R-HSA-381426 | Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| reactome | R-HSA-392499 | Metabolism of proteins |
| reactome | R-HSA-446203 | Asparagine N-linked glycosylation |
| reactome | R-HSA-5653656 | Vesicle-mediated transport |
| reactome | R-HSA-5694530 | Cargo concentration in the ER |
| reactome | R-HSA-597592 | Post-translational protein modification |
| reactome | R-HSA-8957275 | Post-translational protein phosphorylation |
| reactome | R-HSA-948021 | Transport to the Golgi and subsequent modification |
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD705 | Nakiterpiosin | 3 |
| iGMDRD434 | BMS-536924 | 6 |
| iGMDRD415 | LE-135 | 1 |
| iGMDRD213 | SMR000068650 | 2 |
| iGMDRD267 | Oligomycin A | 2 |
| iGMDRD103 | SN-38 | 3 |
| iGMDRD220 | fumonisin B1 | 3 |
| iGMDRD121 | GMX1778 | 3 |
| iGMDRD137 | Indisulam | 6 |
| iGMDRD300 | Tozasertib | 2 |
| iGMDRD147 | Prima-1 | 2 |
| iGMDRD246 | NPC26 | 4 |
| iGMDRD322 | FK 866 | 2 |
| iGMDRD414 | MST-312 | 3 |
| iGMDRD286 | Nsc 632839 | 2 |
| iGMDRD367 | Ro 28-1675 | 2 |
| iGMDRD871 | BRD6368 | 3 |
| iGMDRD872 | BRD7137 | 3 |
| iGMDRD662 | JQ-1 | 3 |
| iGMDRD424 | Tamatinib | 1 |
| iGMDRD345 | Compound 10b [PMID: 11504634] | 3 |
| iGMDRD701 | NVP-AUY922 | 3 |
| iGMDRD512 | nutlin 3 | 4 |
| iGMDRD901 | ELCPK | 3 |
| iGMDRD123 | Isoevodiamine | 3 |
| iGMDRD945 | ML214 | 1 |
| iGMDRD351 | GW843682X | 3 |
| iGMDRD237 | ABT-751 | 3 |
| iGMDRD782 | DC-45-A2 | 1 |
| iGMDRD294 | Batimastat | 1 |
| iGMDRD513 | BML-259 | 3 |
| iGMDRD270 | Ciclosporin | 2 |
| iGMDRD247 | Blebbistatin | 3 |
| iGMDRD260 | FQI-2 | 3 |
| iGMDRD255 | SB225002 | 2 |
| iGMDRD802 | 4-methylfasudil | 3 |
| iGMDRD64 | Parbendazole | 2 |
| iGMDRD23 | Gossypol | 2 |
| iGMDRD524 | ISX-9 | 2 |
| iGMDRD188 | Piperlongumine | 4 |
| iGMDRD100 | Zebularine | 4 |
| iGMDRD887 | Compound 23 citrate | 2 |
| iGMDRD399 | Selumetinib | 2 |
| iGMDRD74 | Idarubicin | 2 |
| iGMDRD577 | BIX01294 | 2 |
| iGMDRD398 | Sepantronium | 3 |
| iGMDRD562 | Navitoclax | 6 |
| iGMDRD427 | ABT737 | 3 |
| iGMDRD546 | BMS-754807 | 2 |
| iGMDRD781 | Sirolimus | 5 |
| iGMDRD126 | Tipifarnib | 5 |
| iGMDRD151 | CHM-1 | 3 |
| iGMDRD1008 | SR-II-138A | 2 |
| iGMDRD579 | PF750 | 4 |
| iGMDRD394 | BX-795 | 3 |
| iGMDRD466 | Chaetocin | 3 |
| iGMDRD634 | SCHEMBL2608041 | 1 |
| iGMDRD446 | LY 2183240 | 6 |
| iGMDRD316 | N9-Isopropyl-olomoucine | 1 |
| iGMDRD639 | YK 4-279 | 1 |
| iGMDRD193 | Fqi1 | 4 |
| iGMDRD61 | Kinetin riboside | 3 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in MIA3
CLASSFICATION
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