RALGDS
Summary: Guanine nucleotide dissociation stimulators (GDSs, or exchange factors), such as RALGDS, are effectors of Ras-related GTPases (see MIM 190020) that participate in signaling for a variety of cellular processes.[supplied by OMIM, Nov 2010].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:601619 Ensembl IDEnsembl:ENSG00000160271 HGNC IDHGNC:HGNC:9842 PHARMGKB IDPA34200 Map Location9q34.13-q34.2 | |||||
GO terms in RALGDS
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | TAS | GO:0007265 | Ras protein signal transduction |
| BP | IEA | GO:0050790 | regulation of catalytic activity |
| CC | IDA | GO:0005634 | nucleus |
| CC | IDA | GO:0005829 | cytosol |
| CC | TAS | GO:0005829 | cytosol |
| CC | IDA | GO:0005903 | brush border |
Gene expression in normal tissue: RALGDS
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in RALGDS
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| wikipathways | WP2032 | Human Thyroid Stimulating Hormone (TSH) signaling pathway |
| wikipathways | WP4216 | Chromosomal and microsatellite instability in colorectal cancer |
| wikipathways | WP4223 | Ras Signaling |
| wikipathways | WP437 | EGF-EGFR Signaling Pathway |
| pid | erbb1_downstream_pathway | ErbB1 downstream signaling |
| kegg | hsa04014 | Ras signaling pathway - Homo sapiens (human) |
Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in RALGDS
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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