ZNF497
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| zinc finger protein 497 | Ensembl:ENSG00000174586 | HGNC:HGNC:23714 | PA134994387 | 19q13.43 |
GO terms in ZNF497
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | ISA | GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding |
| MF | IEA | GO:0003677 | DNA binding |
| MF | IBA | GO:0003700 | DNA-binding transcription factor activity |
| MF | IBA | GO:0044212 | transcription regulatory region DNA binding |
| MF | IEA | GO:0046872 | metal ion binding |
| CC | IEA | GO:0005634 | nucleus |
| CC | IBA | GO:0005654 | nucleoplasm |
| BP | IBA | GO:0000122 | negative regulation of transcription by RNA polymerase II |
| BP | IEA | GO:0006351 | transcription, DNA-templated |
| BP | IEA | GO:0006357 | regulation of transcription by RNA polymerase II |
| BP | IBA | GO:0045944 | positive regulation of transcription by RNA polymerase II |
Gene expression in normal tissue: ZNF497
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in ZNF497
| Database | Pathway ID | Pathway Des. |
|---|
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD512 | nutlin 3 | 3 |
| iGMDRD126 | Tipifarnib | 3 |
| iGMDRD415 | LE-135 | 3 |
| iGMDRD481 | Dactolisib | 3 |
| iGMDRD560 | MK-2206 | 3 |
| iGMDRD506 | Fedratinib | 3 |
| iGMDRD329 | Merck60 | 2 |
| iGMDRD23 | Gossypol | 3 |
| iGMDRD353 | PD0325901 | 1 |
| iGMDRD369 | TGX-115 | 3 |
| iGMDRD123 | Isoevodiamine | 3 |
| iGMDRD177 | Teniposide | 3 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in ZNF497
CLASSFICATION
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