HORMAD1
Summary: This gene encodes a HORMA domain-containing protein. HORMA domains are involved in chromatin binding and play a role in cell cycle regulation. The encoded protein may play a role in meiosis, and expression of this gene is a potential marker for cancer. A pseudogene of this gene is located on the long arm of chromosome 6. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010].
Loading, please wait...
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:609824 Ensembl IDEnsembl:ENSG00000143452 HGNC IDHGNC:HGNC:25245 PHARMGKB IDPA134930374 Map Location1q21.3 | |||||
Gene Categories:
TUMOR SUPPRESSORGO terms in HORMAD1
Loading, please wait...
Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | ISS | GO:0001824 | blastocyst development |
| BP | ISS | GO:0007130 | synaptonemal complex assembly |
| BP | ISS | GO:0007283 | spermatogenesis |
| BP | ISS | GO:0042138 | meiotic DNA double-strand break formation |
| BP | ISS | GO:0048477 | oogenesis |
| BP | ISS | GO:0051177 | meiotic sister chromatid cohesion |
Gene expression in normal tissue: HORMAD1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in HORMAD1
Loading, please wait...
Database | Pathway ID | Pathway Des. |
|---|---|---|
| No matching records found | ||
Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in HORMAD1
Loading, please wait...
Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
Copyright © 2018 Modellab | All Rights Reserved
Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.