CTNNA2


Summary:

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
catenin alpha 2MIM:114025Ensembl:ENSG00000066032HGNC:HGNC:2510PA270092p12

GO terms in CTNNA2


Term TypeEvidence TypeGO Term IDGO Des.
MFNASGO:0005200structural constituent of cytoskeleton
MFIPIGO:0005515protein binding
MFIEAGO:0042802identical protein binding
MFHDAGO:0045296cadherin binding
MFIEAGO:0051015actin filament binding
CCIEAGO:0005634nucleus
CCIDAGO:0005737cytoplasm
CCTASGO:0005829cytosol
CCISSGO:0005912adherens junction
CCIEAGO:0005913cell-cell adherens junction
CCIEAGO:0014069postsynaptic density
CCIEAGO:0015629actin cytoskeleton
CCIEAGO:0016323basolateral plasma membrane
CCIEAGO:0030027lamellipodium
CCISSGO:0030424axon
BPIEAGO:0007010cytoskeleton organization
BPISSGO:0007409axonogenesis
BPISSGO:0021942radial glia guided migration of Purkinje cell
BPISSGO:0048813dendrite morphogenesis
BPISSGO:0048854brain morphogenesis
BPTASGO:0051149positive regulation of muscle cell differentiation
BPISSGO:0051823regulation of synapse structural plasticity
BPISSGO:0060134prepulse inhibition
BPISSGO:0098609cell-cell adhesion

Gene expression in normal tissue: CTNNA2

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in CTNNA2


DatabasePathway IDPathway Des.
reactomeR-HSA-1266738Developmental Biology
reactomeR-HSA-1266738Developmental Biology
reactomeR-HSA-375170CDO in myogenesis
reactomeR-HSA-375170CDO in myogenesis
reactomeR-HSA-525793Myogenesis
reactomeR-HSA-525793Myogenesis
netpathPathway_TGF_beta_ReceptorTGF_beta_Receptor
kegghsa04390Hippo signaling pathway - Homo sapiens (human)
kegghsa04520Adherens junction - Homo sapiens (human)
kegghsa04670Leukocyte transendothelial migration - Homo sapiens (human)
kegghsa05100Bacterial invasion of epithelial cells - Homo sapiens (human)
kegghsa05200Pathways in cancer - Homo sapiens (human)
kegghsa05213Endometrial cancer - Homo sapiens (human)
kegghsa05226Gastric cancer - Homo sapiens (human)
kegghsa05412Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human)
wikipathwaysWP2118Arrhythmogenic Right Ventricular Cardiomyopathy
wikipathwaysWP2858Ectoderm Differentiation
wikipathwaysWP4155Endometrial cancer

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD433Lexibulin3
iGMDRD151CHM-15
iGMDRD554CHEMBL14341373
iGMDRD889Compound 7d-cis1
iGMDRD772BRD47703
iGMDRD144NSC953971
iGMDRD427ABT7377
iGMDRD781Sirolimus7
iGMDRD446LY 21832401
iGMDRD201SKI II2
iGMDRD152179324-69-77
iGMDRD61Kinetin riboside1
iGMDRD193Fqi14
iGMDRD297Austocystin D2
iGMDRD280CYTOCHALASIN B1
iGMDRD394BX-7952
iGMDRD375GW-4058333
iGMDRD260FQI-25
iGMDRD782DC-45-A24
iGMDRD318PAC-14
iGMDRD885Compound 1104
iGMDRD577BIX012941
iGMDRD888Compound 442
iGMDRD562Navitoclax9
iGMDRD64Parbendazole3
iGMDRD23Gossypol1
iGMDRD524ISX-93
iGMDRD84Lovastatin acid6
iGMDRD307Manumycin A3
iGMDRD512nutlin 33
iGMDRD148Pifithrin-mu2
iGMDRD532Olaparib1
iGMDRD424Tamatinib3
iGMDRD583LDN 1931891
iGMDRD701NVP-AUY9223
iGMDRD698Neratinib3
iGMDRD499PDMP1
iGMDRD351GW843682X3
iGMDRD57Chloropentafluorobenzene4
iGMDRD237ABT-7512
iGMDRD901ELCPK3
iGMDRD123Isoevodiamine7
iGMDRD132(-)-gallocatechin-3-O-gallate3
iGMDRD271Brefeldin A1
iGMDRD202Curcumin2
iGMDRD121GMX17783
iGMDRD221Tamoxifen6
iGMDRD705Nakiterpiosin2
iGMDRD105Triptolide2
iGMDRD415LE-1351
iGMDRD481Dactolisib6
iGMDRD871BRD63681
iGMDRD286Nsc 6328395
iGMDRD872BRD71373
iGMDRD886Compound 1541A3
iGMDRD300Tozasertib2
iGMDRD147Prima-11
iGMDRD82Quiflapon4

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in CTNNA2

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