CTNNA2
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| catenin alpha 2 | MIM:114025 | Ensembl:ENSG00000066032 | HGNC:HGNC:2510 | PA27009 | 2p12 |
GO terms in CTNNA2
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | NAS | GO:0005200 | structural constituent of cytoskeleton |
| MF | IPI | GO:0005515 | protein binding |
| MF | IEA | GO:0042802 | identical protein binding |
| MF | HDA | GO:0045296 | cadherin binding |
| MF | IEA | GO:0051015 | actin filament binding |
| CC | IEA | GO:0005634 | nucleus |
| CC | IDA | GO:0005737 | cytoplasm |
| CC | TAS | GO:0005829 | cytosol |
| CC | ISS | GO:0005912 | adherens junction |
| CC | IEA | GO:0005913 | cell-cell adherens junction |
| CC | IEA | GO:0014069 | postsynaptic density |
| CC | IEA | GO:0015629 | actin cytoskeleton |
| CC | IEA | GO:0016323 | basolateral plasma membrane |
| CC | IEA | GO:0030027 | lamellipodium |
| CC | ISS | GO:0030424 | axon |
| BP | IEA | GO:0007010 | cytoskeleton organization |
| BP | ISS | GO:0007409 | axonogenesis |
| BP | ISS | GO:0021942 | radial glia guided migration of Purkinje cell |
| BP | ISS | GO:0048813 | dendrite morphogenesis |
| BP | ISS | GO:0048854 | brain morphogenesis |
| BP | TAS | GO:0051149 | positive regulation of muscle cell differentiation |
| BP | ISS | GO:0051823 | regulation of synapse structural plasticity |
| BP | ISS | GO:0060134 | prepulse inhibition |
| BP | ISS | GO:0098609 | cell-cell adhesion |
Gene expression in normal tissue: CTNNA2
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in CTNNA2
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-1266738 | Developmental Biology |
| reactome | R-HSA-1266738 | Developmental Biology |
| reactome | R-HSA-375170 | CDO in myogenesis |
| reactome | R-HSA-375170 | CDO in myogenesis |
| reactome | R-HSA-525793 | Myogenesis |
| reactome | R-HSA-525793 | Myogenesis |
| netpath | Pathway_TGF_beta_Receptor | TGF_beta_Receptor |
| kegg | hsa04390 | Hippo signaling pathway - Homo sapiens (human) |
| kegg | hsa04520 | Adherens junction - Homo sapiens (human) |
| kegg | hsa04670 | Leukocyte transendothelial migration - Homo sapiens (human) |
| kegg | hsa05100 | Bacterial invasion of epithelial cells - Homo sapiens (human) |
| kegg | hsa05200 | Pathways in cancer - Homo sapiens (human) |
| kegg | hsa05213 | Endometrial cancer - Homo sapiens (human) |
| kegg | hsa05226 | Gastric cancer - Homo sapiens (human) |
| kegg | hsa05412 | Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human) |
| wikipathways | WP2118 | Arrhythmogenic Right Ventricular Cardiomyopathy |
| wikipathways | WP2858 | Ectoderm Differentiation |
| wikipathways | WP4155 | Endometrial cancer |
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD433 | Lexibulin | 3 |
| iGMDRD151 | CHM-1 | 5 |
| iGMDRD554 | CHEMBL1434137 | 3 |
| iGMDRD889 | Compound 7d-cis | 1 |
| iGMDRD772 | BRD4770 | 3 |
| iGMDRD144 | NSC95397 | 1 |
| iGMDRD427 | ABT737 | 7 |
| iGMDRD781 | Sirolimus | 7 |
| iGMDRD446 | LY 2183240 | 1 |
| iGMDRD201 | SKI II | 2 |
| iGMDRD152 | 179324-69-7 | 7 |
| iGMDRD61 | Kinetin riboside | 1 |
| iGMDRD193 | Fqi1 | 4 |
| iGMDRD297 | Austocystin D | 2 |
| iGMDRD280 | CYTOCHALASIN B | 1 |
| iGMDRD394 | BX-795 | 2 |
| iGMDRD375 | GW-405833 | 3 |
| iGMDRD260 | FQI-2 | 5 |
| iGMDRD782 | DC-45-A2 | 4 |
| iGMDRD318 | PAC-1 | 4 |
| iGMDRD885 | Compound 110 | 4 |
| iGMDRD577 | BIX01294 | 1 |
| iGMDRD888 | Compound 44 | 2 |
| iGMDRD562 | Navitoclax | 9 |
| iGMDRD64 | Parbendazole | 3 |
| iGMDRD23 | Gossypol | 1 |
| iGMDRD524 | ISX-9 | 3 |
| iGMDRD84 | Lovastatin acid | 6 |
| iGMDRD307 | Manumycin A | 3 |
| iGMDRD512 | nutlin 3 | 3 |
| iGMDRD148 | Pifithrin-mu | 2 |
| iGMDRD532 | Olaparib | 1 |
| iGMDRD424 | Tamatinib | 3 |
| iGMDRD583 | LDN 193189 | 1 |
| iGMDRD701 | NVP-AUY922 | 3 |
| iGMDRD698 | Neratinib | 3 |
| iGMDRD499 | PDMP | 1 |
| iGMDRD351 | GW843682X | 3 |
| iGMDRD57 | Chloropentafluorobenzene | 4 |
| iGMDRD237 | ABT-751 | 2 |
| iGMDRD901 | ELCPK | 3 |
| iGMDRD123 | Isoevodiamine | 7 |
| iGMDRD132 | (-)-gallocatechin-3-O-gallate | 3 |
| iGMDRD271 | Brefeldin A | 1 |
| iGMDRD202 | Curcumin | 2 |
| iGMDRD121 | GMX1778 | 3 |
| iGMDRD221 | Tamoxifen | 6 |
| iGMDRD705 | Nakiterpiosin | 2 |
| iGMDRD105 | Triptolide | 2 |
| iGMDRD415 | LE-135 | 1 |
| iGMDRD481 | Dactolisib | 6 |
| iGMDRD871 | BRD6368 | 1 |
| iGMDRD286 | Nsc 632839 | 5 |
| iGMDRD872 | BRD7137 | 3 |
| iGMDRD886 | Compound 1541A | 3 |
| iGMDRD300 | Tozasertib | 2 |
| iGMDRD147 | Prima-1 | 1 |
| iGMDRD82 | Quiflapon | 4 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in CTNNA2
CLASSFICATION
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