DLL1
Summary: DLL1 is a human homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family. It plays a role in mediating cell fate decisions during hematopoiesis. It may play a role in cell-to-cell communication. [provided by RefSeq, Jul 2008].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:606582 Ensembl IDEnsembl:ENSG00000198719 HGNC IDHGNC:HGNC:2908 PHARMGKB IDPA27364 Map Location6q27 | |||||
Gene Categories:
TRANSCRIPTION FACTOR BINDINGGO terms in DLL1
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | NAS | GO:0001709 | cell fate determination |
| BP | ISS | GO:0001756 | somitogenesis |
| BP | IEA | GO:0001757 | somite specification |
| BP | ISS | GO:0001947 | heart looping |
| BP | ISS | GO:0002315 | marginal zone B cell differentiation |
| BP | ISS | GO:0003323 | type B pancreatic cell development |
Gene expression in normal tissue: DLL1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in DLL1
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| biocarta | hespathway | segmentation clock |
| biocarta | notchpathway | proteolysis and signaling pathway of notch |
| reactome | R-HSA-157118 | Signaling by NOTCH |
| reactome | R-HSA-157118 | Signaling by NOTCH |
| reactome | R-HSA-162582 | Signal Transduction |
| reactome | R-HSA-162582 | Signal Transduction |
Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in DLL1
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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