iGMDRD314

Canonical SMILES: CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)NCC=C)C)OC)OC(=O)N)C)C)O)OC

InChI: InChI=1S/C31H43N3O8/c1-8-12-33-26-21-13-17(2)14-25(41-7)27(36)19(4)15-20(5)29(42-31(32)39)24(40-6)11-9-10-18(3)30(38)34-22(28(21)37)16-23(26)35/h8-11,15-17,19,24-25,27,29,33,36H,1,12-14H2,2-7H3,(H2,32,39)(H,34,38)/b11-9-,18-10+,20-15+/t17-,19+,24+,25+,27-,29+/m1/s1

InChI Key: AYUNIORJHRXIBJ-TXHRRWQRSA-N

Standard NameCHEMBLPubchem CIDDRUGBANK IDDrug StatusDrug Type
TanespimycinCHEMBL109480 6505800DB05134AloneSmall Molecule



Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


Gene IDGene NameModel Num.
3696ITGB85
64901RANBP171
4854NOTCH32
10460TACC35
7535ZAP701
7837PXDN1
79054TRPM83
132ADK2
26191PTPN221
11183MAP4K55
220064LTO12
150465TTL4
4750NEK11
6351CCL42
3939LDHA3
11193WBP45
4312MMP11
10395DLC17
353345GPR1414
3209HOXA133
9530BAG42
64783RBM153
6598SMARCB13
1607DGKB2
7253TSHR3
23310NCAPD31
57172CAMK1G4
6455SH3GL13
6887TAL25
114908TMEM1233
7048TGFBR24
2249FGF42
577ADGRB32
114783LMTK31
202374STK32A3
55023PHIP3
10013HDAC64
3055HCK2
1111CHEK13
26576SRPK33
2977GUCY1A22
23617TSSK24
5166PDK41
139378ADGRG43
2033EP3002
8030CCDC61
54477PLEKHA51
2115ETV12
4301AFDN2
25937WWTR11
5607MAP2K51
256646NUTM13
9693RAPGEF21
9175MAP3K132
5468PPARG2
116986AGAP21
23255MTCL12
114548NLRP32
5984RFC43
10188TNK22
10217CTDSPL3
83990BRIP12
1992SERPINB14
65266WNK42
83983TSSK62
834CASP11
29775CARD102
9759HDAC42
92ACVR2A1
1452CSNK1A13
8714ABCC33
65987KCTD146
158056MAMDC42
6793STK101
5591PRKDC3
5568PRKACG3
659BMPR21
9472AKAP63
2778GNAS4
472ATM3
28996HIPK21
4058LTK2
6792CDKL52
5289PIK3C32
898CCNE11
7681MKRN39
5863RGL21
2201FBN21
1029CDKN2A1
7184HSP90B13
27436EML45
157753TMEM742
2868GRK45
28514DLL13
7157TP532
4857NOVA11
5910RAP1GDS13
4086SMAD11
8833GMPS3
863CBFA2T35
1555CYP2B62
9088PKMYT13
7038TG4
9965FGF195
6197RPS6KA33
4436MSH21
4026LPP3
10499NCOA21
23269MGA2
256536TCERG1L1
9252RPS6KA51
78989COLEC111
546ATRX2
5606MAP2K32
5578PRKCA3
440275EIF2AK42
1198CLK33
2187FANCB2
6046BRD25
3720JARID23
2931GSK3A7
4145MATK3
26524LATS21
744MPPED22
7297TYK23
6776STAT5A4
5156PDGFRA5
93627TBCK2
137872ADHFE13
3949LDLR3
6011GRK11
6095RORA5
57507ZNF6083
7468NSD22
5128CDK172
9321TRIP112
664BNIP35
157GRK31
9509ADAMTS22
266747RGL41
23598PATZ12
5728PTEN3
1487CTBP12
2316FLNA2
1869E2F11
3554IL1R11
6146RPL223
2264FGFR43
1676DFFA3
6498SKIL8
8522GAS72
91807MYLK32
6789STK43
7454WAS2
10257ABCC43
203447NRK5
9372ZFYVE92
8821INPP4B3
221895JAZF13
5291PIK3CB3
2932GSK3B2
2869GRK52
10111RAD502
3181HNRNPA2B17
3557IL1RN2
23139MAST21
7099TLR41
5506PPP1R3A2
4772NFATC15
3552IL1A2
4261CIITA3
3656IRAK21
8536CAMK13
3815KIT2
6653SORL13
2903GRIN2A3
5925RB12
5324PLAG12
862RUNX1T16
7403KDM6A1
54790TET23
8717TRADD3
197259MLKL2
5586PKN23
4205MEF2A2
3488IGFBP53
2011MARK23
4299AFF13
2261FGFR34
865CBFB3
2073ERCC51
84446BRSK13
79966SCD52
595CCND12
1612DAPK12
1840DTX12
65975STK334
10891PPARGC1A3
94ACVRL11
7294TXK3
5885RAD213
1499CTNNB18
27151CPAMD83
64328XPO43
56155TEX142
4916NTRK34
5970RELA1

Gene in drug-gene network: Network Plot

Models in Tanespimycin

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