XPO4
Summary: XPO4 belongs to a large family of karyopherins (see MIM 602738) that mediate the transport of proteins and other cargo between the nuclear and cytoplasmic compartments (Lipowsky et al., 2000 [PubMed 10944119]).[supplied by OMIM, Mar 2009].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
Nameexportin 4 OMIM IDMIM:611449 Ensembl IDEnsembl:ENSG00000132953 HGNC IDHGNC:HGNC:17796 PHARMGKB IDPA134866468 Map Location13q12.11 | |||||
Gene Categories:
TRANSPORTERGO terms in XPO4
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | IBA | GO:0005643 | nuclear pore |
| CC | IDA | GO:0005654 | nucleoplasm |
| CC | IBA | GO:0005737 | cytoplasm |
| CC | IDA | GO:0005829 | cytosol |
| BP | IBA | GO:0006611 | protein export from nucleus |
| BP | IEA | GO:0015031 | protein transport |
Gene expression in normal tissue: XPO4
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in XPO4
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| netpath | Pathway_TGF_beta_Receptor | TGF_beta_Receptor |
| wikipathways | WP3302 | eIF5A regulation in response to inhibition of the nuclear export system |
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Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in XPO4
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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