LTO1
Summary:
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
LTO1, ABCE1 maturation factor | MIM:607224 | Ensembl:ENSG00000149716 | HGNC:HGNC:17589 | PA38242 | 11q13.3 |
GO terms in LTO1
Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
MF | ND | GO:0003674 | molecular_function |
BP | IBA | GO:0000724 | double-strand break repair via homologous recombination |
BP | IBA | GO:0006289 | nucleotide-excision repair |
BP | ND | GO:0008150 | biological_process |
BP | IBA | GO:0031573 | intra-S DNA damage checkpoint |
BP | IBA | GO:0033314 | mitotic DNA replication checkpoint |
BP | IBA | GO:0044778 | meiotic DNA integrity checkpoint |
CC | ND | GO:0005575 | cellular_component |
CC | IBA | GO:0030896 | checkpoint clamp complex |
CC | IBA | GO:0035861 | site of double-strand break |
Gene expression in normal tissue: LTO1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in LTO1
Database | Pathway ID | Pathway Des. |
---|
Gene-Drug: Aster Plot
Drug ID | Drug Name | Model Num. |
---|---|---|
iGMDRD434 | BMS-536924 | 1 |
iGMDRD144 | NSC95397 | 2 |
iGMDRD652 | UNC0638 | 3 |
iGMDRD23 | Gossypol | 3 |
iGMDRD871 | BRD6368 | 3 |
iGMDRD314 | Tanespimycin | 2 |
iGMDRD577 | BIX01294 | 1 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in LTO1