GAS7


Summary: Growth arrest-specific 7 is expressed primarily in terminally differentiated brain cells and predominantly in mature cerebellar Purkinje neurons. GAS7 plays a putative role in neuronal development. Several transcript variants encoding proteins which vary in the N-terminus have been described. [provided by RefSeq, Jul 2008].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
growth arrest specific 7MIM:603127Ensembl:ENSG00000007237HGNC:HGNC:4169PA2858317p13.1

Gene Categories:

TUMOR SUPPRESSOR

GO terms in GAS7


Term TypeEvidence TypeGO Term IDGO Des.
BPIEAGO:0006355regulation of transcription, DNA-templated
BPIBAGO:0007010cytoskeleton organization
BPTASGO:0007050cell cycle arrest
BPIEAGO:0007399nervous system development
BPIBAGO:0030041actin filament polymerization
BPIEAGO:0030154cell differentiation
BPIBAGO:0030182neuron differentiation
BPIBAGO:0048812neuron projection morphogenesis
CCIBAGO:0005737cytoplasm
CCIEAGO:0005737cytoplasm
CCIBAGO:0005856cytoskeleton
CCIBAGO:0005884actin filament
CCIBAGO:0005886plasma membrane
MFTASGO:0003700DNA-binding transcription factor activity
MFIPIGO:0005515protein binding
MFIBAGO:0008092cytoskeletal protein binding
MFIBAGO:0051015actin filament binding

Gene expression in normal tissue: GAS7

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in GAS7


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD60Quinoclamine1
iGMDRD552AZD-17753
iGMDRD505Pevonedistat6
iGMDRD780PP-303
iGMDRD562Navitoclax4
iGMDRD77Itraconazole2
iGMDRD267Oligomycin A2
iGMDRD318PAC-11
iGMDRD481Dactolisib2
iGMDRD434BMS-5369242
iGMDRD782DC-45-A22
iGMDRD705Nakiterpiosin2
iGMDRD121GMX17782
iGMDRD202Curcumin4
iGMDRD103SN-382
iGMDRD132(-)-gallocatechin-3-O-gallate2
iGMDRD394BX-7952
iGMDRD280CYTOCHALASIN B4
iGMDRD901ELCPK2
iGMDRD698Neratinib2
iGMDRD314Tanespimycin2
iGMDRD85Ursolic acid3
iGMDRD446LY 21832403
iGMDRD494Neopeltolide2
iGMDRD483SCH-5290741
iGMDRD523Cyanoquinoline, 112
iGMDRD427ABT7372

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in GAS7

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