GAS7


Summary: Growth arrest-specific 7 is expressed primarily in terminally differentiated brain cells and predominantly in mature cerebellar Purkinje neurons. GAS7 plays a putative role in neuronal development. Several transcript variants encoding proteins which vary in the N-terminus have been described. [provided by RefSeq, Jul 2008].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
OMIM IDMIM:603127
PHARMGKB IDPA28583
Map Location17p13.1

Gene Categories:

TUMOR SUPPRESSOR

GO terms in GAS7


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Term Type
Evidence Type
GO Term ID
GO Des.
BP IEA GO:0006355 regulation of transcription, DNA-templated
BP IBA GO:0007010 cytoskeleton organization
BP TAS GO:0007050 cell cycle arrest
BP IEA GO:0007399 nervous system development
BP IBA GO:0030041 actin filament polymerization
BP IEA GO:0030154 cell differentiation
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Gene expression in normal tissue: GAS7

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

undefined21Apoptosis regulation2Protein stability and degradation1DNA replication1PI3K/MTOR signaling1Stilbenoid, diarylheptanoid and gingerol biosynthesis1

Pathways in GAS7


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Database
Pathway ID
Pathway Des.
No matching records found

Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD60 Quinoclamine 1
iGMDRD552 AZD-1775 3
iGMDRD505 Pevonedistat 6
iGMDRD780 PP-30 3
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in GAS7

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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