MGA


Summary:

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location

GO terms in MGA


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Term Type
Evidence Type
GO Term ID
GO Des.
CC TAS GO:0005654 nucleoplasm
CC IDA GO:0071339 MLL1 complex
BP IEA GO:0006351 transcription, DNA-templated
BP IEA GO:0006357 regulation of transcription by RNA polymerase II
BP TAS GO:0070317 negative regulation of G0 to G1 transition
MF ISA GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding
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Gene expression in normal tissue: MGA

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

undefined44Apoptosis regulation4PI3K/MTOR signaling4Other, kinases2Chromatin histone methylation1p53 pathway1Protein stability and degradation1Th17 cell differentiation1Metabolism1Biosynthesis of secondary metabolites1

Pathways in MGA


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Database
Pathway ID
Pathway Des.
reactome R-HSA-212436 Generic Transcription Pathway
reactome R-HSA-73857 RNA Polymerase II Transcription
reactome R-HSA-74160 Gene expression (Transcription)
reactome R-HSA-8953750 Transcriptional Regulation by E2F6
wikipathways WP3651 Pathways Affected in Adenoid Cystic Carcinoma
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD260 FQI-2 5
iGMDRD226 ML006 3
iGMDRD188 Piperlongumine 1
iGMDRD74 Idarubicin 8
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in MGA

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
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