iGMDRD605

Canonical SMILES: CC1=CN2C(=O)C=C(N=C2C(=C1)C(C)NC3=CC=CC=C3C(=O)O)N4CCOCC4

InChI: InChI=1S/C22H24N4O4/c1-14-11-17(15(2)23-18-6-4-3-5-16(18)22(28)29)21-24-19(12-20(27)26(21)13-14)25-7-9-30-10-8-25/h3-6,11-13,15,23H,7-10H2,1-2H3,(H,28,29)/t15-/m1/s1

InChI Key: IRTDIKMSKMREGO-OAHLLOKOSA-N

Standard NamePubchem CIDDrug StatusDrug Type
AZD648244137700AloneSmall Molecule

Drug Targets:

PI3KbetaPIK3CD

Drug Pathways:

PI3K/MTOR signaling

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


Gene IDGene NameModel Num.
3845KRAS1
8289ARID1A1
6597SMARCA41
1786DNMT11
11200CHEK21
2033EP3002
1108CHD41
4301AFDN1
25937WWTR11
2064ERBB21
8503PIK3R31
27332ZNF6381
3932LCK2
58508KMT2C1
4088SMAD31
27086FOXP11
7422VEGFA1
23269MGA1
5290PIK3CA2
2189FANCG1
673BRAF1
6615SNAI11
5728PTEN4
1974EIF4A21
440ASNS1
2072ERCC41
4893NRAS1
7403KDM6A1
5287PIK3C2B1
5624PROC2

Gene in drug-gene network: Network Plot

Models in AZD6482

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