EIF4A2

Summary:

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Nameeukaryotic translation initiation factor 4A2
OMIM IDMIM:601102
Ensembl IDEnsembl:ENSG00000156976
HGNC IDHGNC:HGNC:3284
PHARMGKB IDPA27712
Map Location3q27.3

GO terms in EIF4A2


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Term Type
Evidence Type
GO Term ID
GO Des.
MF HDA GO:0003723 RNA binding
MF IEA GO:0003743 translation initiation factor activity
MF TAS GO:0004386 helicase activity
MF IPI GO:0005515 protein binding
MF IEA GO:0005524 ATP binding
MF IDA GO:0016887 ATPase activity
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Gene expression in normal tissue: EIF4A2

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in EIF4A2


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Database
Pathway ID
Pathway Des.
reactome R-HSA-1169408 ISG15 antiviral mechanism
reactome R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes
reactome R-HSA-1280215 Cytokine Signaling in Immune system
reactome R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression
reactome R-HSA-168256 Immune System
reactome R-HSA-392499 Metabolism of proteins
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD882 CIL41 3
iGMDRD133 Lapatinib 1
iGMDRD188 Piperlongumine 2
iGMDRD67 PENFLURIDOL 3
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in EIF4A2

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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