iGMDRD599


Canonical SMILES: CC(C1=CC=CC=C1)C(=O)NC2=CC=CC(=C2)NC=C3C(=O)C=CC4=CC=CC=C43

InChI: InChI=1S/C26H22N2O2/c1-18(19-8-3-2-4-9-19)26(30)28-22-12-7-11-21(16-22)27-17-24-23-13-6-5-10-20(23)14-15-25(24)29/h2-18,27H,1H3,(H,28,30)/b24-17-

InChI Key: UADRPWLRVLBVBC-ULJHMMPZSA-N

Standard NamePubchem CIDDrug StatusDrug Type
Salermide42626400AloneSmall Molecule

Drug Targets:

SIRT1SIRT2

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


Gene IDGene NameModel Num.
331XIAP2
1147CHUK2
1105CHD13
4854NOTCH34
7074TIAM13
5027P2RX71
10903MTMR111
79848CSPP11
7535ZAP703
79054TRPM81
10987COPS53
21ABCA34
6195RPS6KA16
2986GUCY2F1
114801TMEM200A2
2956MSH63
57679ALS24
7272TTK3
3845KRAS3
2100ESR26
8289ARID1A2
25778DSTYK3
4928NUP981
9475ROCK21
6597SMARCA41
10395DLC14
5133PDCD11
6657SOX23
390502SERPINA25
56776FMN21
64783RBM151
10892MALT12
23235SIK22
3320HSP90AA14
10142AKAP91
55781RIOK23
7253TSHR3
23310NCAPD34
3195TLX16
27ABL23
1404HAPLN16
2623GATA16
7048TGFBR22
1387CREBBP1
2043EPHA42
5788PTPRC3
4283CXCL96
9411ARHGAP293
8295TRRAP2
2977GUCY1A24
27148STK363
5166PDK43
55294FBXW71
2033EP3003
6927HNF1A2
641BLM1
23522KAT6B2
55728N4BP22
4610MYCL5
816CAMK2B3
84033OBSCN4
152137CCDC502
1540CYLD2
8767RIPK23
32ACACB2
26353HSPB86
2242FES6
22984PDCD113
9175MAP3K133
200576PIKFYVE5
80351TNKS23
8313AXIN24
6733SRPK22
23255MTCL14
730249ACOD13
9636ISG153
2736GLI23
83990BRIP11
55681SCYL21
2045EPHA71
238ALK2
85443DCLK33
54899PXK4
338322NLRP103
1456CSNK1G33
6416MAP2K47
9759HDAC41
8714ABCC33
64170CARD96
10087COL4A3BP1
8859STK193
8091HMGA26
6464SHC16
7507XPA6
6098ROS11
3667IRS13
8945BTRC3
139285AMER14
8148TAF155
1123CHN16
91461PKDCC3
2066ERBB41
10290SPEG2
10062NR1H33
27436EML42
57523NYNRIN3
28514DLL13
648BMI13
7157TP536
25836NIPBL1
2329FMO45
114788CSMD34
1019CDK41
9967THRAP36
8833GMPS1
8874ARHGEF73
55034MOCOS3
10516FBLN56
5077PAX32
9965FGF191
7175TPR1
5871MAP4K22
9401RECQL43
80205CHD95
2000ELF43
57578UNC792
4026LPP3
2071ERCC31
6654SOS12
2737GLI33
78989COLEC112
23373CRTC15
285220EPHA63
51366UBR53
3417IDH11
85414SLC45A36
5297PI4KA7
57144PAK52
2187FANCB3
50615IL21R2
84823LMNB23
5290PIK3CA3
3720JARID23
7043TGFB33
3458IFNG1
26166RGS223
7075TIE15
1956EGFR3
2735GLI13
4609MYC1
64333ARHGAP91
5789PTPRD1
8021NUP2142
10461MERTK1
26278SACS2
894CCND22
5462POU5F1B5
6446SGK16
204851HIPK13
3635INPP5D5
91754NEK93
27330RPS6KA65
6872TAF15
673BRAF6
57082KNL14
84630TTBK12
1213CLTC1
6011GRK12
84879MFSD2A2
1769DNAH87
22976PAXIP12
23532PRAME1
4863NPAT3
120892LRRK25
7027TFDP13
867CBL3
6095RORA1
5205ATP8B13
11184MAP4K13
9113LATS12
5979RET6
9843HEPH6
157GRK33
9509ADAMTS21
23742NPAP12
8312AXIN15
1806DPYD3
7155TOP2B2
55120FANCL1
1869E2F13
80124VCPIP13
1974EIF4A23
115701ALPK23
3554IL1R13
2897GRIK11
6770STAR2
1950EGF2
2264FGFR43
177AGER6
7042TGFB26
995CDC25C3
85415RHPN25
2277VEGFD5
54861SNRK2
10249GLYAT1
57820CCNB1IP13
57680CHD81
5923RASGRF12
1399CRKL3
9021SOCS32
1789DNMT3B3
53353LRP1B4
7094TLN13
5609MAP2K72
1281COL3A15
1385CREB11
55007FAM118A3
5583PRKCH1
3717JAK23
3709ITPR22
4221MEN13
8899PRPF4B2
8550MAPKAPK53
65267WNK33
3977LIFR4
4330MN14
170685NUDT103
5087PBX11
3815KIT1
9212AURKB6
2903GRIN2A3
5925RB11
10420TESK24
7403KDM6A1
7508XPC1
197259MLKL3
255239ANKK13
7040TGFB12
30849PIK3R41
55959SULF21
2011MARK22
142PARP12
4841NONO3
8321FZD13
55791LRIF12
9625AATK3
57096RPGRIP12
2178FANCE4
83732RIOK12
3895KTN13
2892GRIA33
5590PRKCZ2

Gene in drug-gene network: Network Plot

Models in Salermide

​​​​