RIOK1
Summary: The protein encoded by this gene competes with pICln for inclusion in the protein arginine methyltransferase 5 complex. This complex targets substrates for dimethylation. The encoded protein is essential for the last steps in the maturation of 40S subunits. [provided by RefSeq, Jan 2017].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
NameRIO kinase 1 OMIM IDMIM:617753 Ensembl IDEnsembl:ENSG00000124784 HGNC IDHGNC:HGNC:18656 PHARMGKB IDPA134928236 Map Location6p24.3 | |||||
GO terms in RIOK1
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IEA | GO:0004674 | protein serine/threonine kinase activity |
| MF | IPI | GO:0005515 | protein binding |
| MF | IEA | GO:0005524 | ATP binding |
| MF | IEA | GO:0016787 | hydrolase activity |
| MF | IEA | GO:0046872 | metal ion binding |
| BP | IEA | GO:0006468 | protein phosphorylation |
Gene expression in normal tissue: RIOK1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in RIOK1
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-6791226 | Major pathway of rRNA processing in the nucleolus and cytosol |
| reactome | R-HSA-72312 | rRNA processing |
| reactome | R-HSA-8868773 | rRNA processing in the nucleus and cytosol |
| reactome | R-HSA-8953854 | Metabolism of RNA |
| kegg | hsa03008 | Ribosome biogenesis in eukaryotes - Homo sapiens (human) |
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Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in RIOK1
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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