NPAT
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| nuclear protein, coactivator of histone transcription | MIM:601448 | Ensembl:ENSG00000149308 | HGNC:HGNC:7896 | PA31697 | 11q22.3 |
GO terms in NPAT
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | IDA | GO:0005634 | nucleus |
| CC | IDA | GO:0005654 | nucleoplasm |
| CC | IDA | GO:0005737 | cytoplasm |
| CC | IDA | GO:0015030 | Cajal body |
| CC | IDA | GO:0097504 | Gemini of coiled bodies |
| BP | IMP | GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle |
| BP | IEA | GO:0006351 | transcription, DNA-templated |
| BP | IMP | GO:0010468 | regulation of gene expression |
| BP | IDA | GO:0045893 | positive regulation of transcription, DNA-templated |
| BP | IEA | GO:1903507 | negative regulation of nucleic acid-templated transcription |
| MF | IDA | GO:0003713 | transcription coactivator activity |
| MF | IMP | GO:0003713 | transcription coactivator activity |
| MF | IMP | GO:0003714 | transcription corepressor activity |
| MF | IPI | GO:0005515 | protein binding |
| MF | IPI | GO:0008022 | protein C-terminus binding |
| MF | IPI | GO:0047485 | protein N-terminus binding |
Gene expression in normal tissue: NPAT
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD446 | LY 2183240 | 3 |
| iGMDRD193 | Fqi1 | 5 |
| iGMDRD718 | Pyrvinium pamoate | 1 |
| iGMDRD280 | CYTOCHALASIN B | 2 |
| iGMDRD210 | AC55649 | 1 |
| iGMDRD772 | BRD4770 | 3 |
| iGMDRD599 | Salermide | 3 |
| iGMDRD387 | CHIR-99021 | 2 |
| iGMDRD887 | Compound 23 citrate | 2 |
| iGMDRD100 | Zebularine | 4 |
| iGMDRD398 | Sepantronium | 3 |
| iGMDRD577 | BIX01294 | 4 |
| iGMDRD60 | Quinoclamine | 3 |
| iGMDRD138 | PX 12 | 3 |
| iGMDRD782 | DC-45-A2 | 1 |
| iGMDRD870 | BRD63610 | 2 |
| iGMDRD441 | TW 37 | 1 |
| iGMDRD85 | Ursolic acid | 1 |
| iGMDRD211 | (1S,3R)-RSL3 | 3 |
| iGMDRD84 | Lovastatin acid | 2 |
| iGMDRD345 | Compound 10b [PMID: 11504634] | 5 |
| iGMDRD424 | Tamatinib | 3 |
| iGMDRD116 | CD437 | 1 |
| iGMDRD872 | BRD7137 | 2 |
| iGMDRD246 | NPC26 | 6 |
| iGMDRD886 | Compound 1541A | 2 |
| iGMDRD271 | Brefeldin A | 2 |
| iGMDRD434 | BMS-536924 | 3 |
| iGMDRD6 | AM-580 | 3 |
| iGMDRD639 | YK 4-279 | 3 |
| iGMDRD394 | BX-795 | 2 |
| iGMDRD466 | Chaetocin | 3 |
| iGMDRD151 | CHM-1 | 3 |
| iGMDRD126 | Tipifarnib | 2 |
| iGMDRD420 | Leucascandrolide A | 2 |
| iGMDRD779 | PRL-3 Inhibitor I | 2 |
| iGMDRD546 | BMS-754807 | 3 |
| iGMDRD74 | Idarubicin | 5 |
| iGMDRD188 | Piperlongumine | 5 |
| iGMDRD780 | PP-30 | 2 |
| iGMDRD64 | Parbendazole | 5 |
| iGMDRD524 | ISX-9 | 1 |
| iGMDRD23 | Gossypol | 2 |
| iGMDRD356 | PNU-74654 | 2 |
| iGMDRD474 | Avrainvillamide | 4 |
| iGMDRD513 | BML-259 | 3 |
| iGMDRD260 | FQI-2 | 2 |
| iGMDRD294 | Batimastat | 2 |
| iGMDRD341 | Triacsin c | 3 |
| iGMDRD123 | Isoevodiamine | 5 |
| iGMDRD945 | ML214 | 2 |
| iGMDRD248 | BRD4354 | 2 |
| iGMDRD150 | RITA | 5 |
| iGMDRD583 | LDN 193189 | 1 |
| iGMDRD367 | Ro 28-1675 | 3 |
| iGMDRD871 | BRD6368 | 2 |
| iGMDRD329 | Merck60 | 4 |
| iGMDRD263 | AACOCF3 | 2 |
| iGMDRD322 | FK 866 | 3 |
| iGMDRD121 | GMX1778 | 4 |
| iGMDRD137 | Indisulam | 5 |
| iGMDRD289 | Parthenolide | 2 |
| iGMDRD705 | Nakiterpiosin | 2 |
| iGMDRD105 | Triptolide | 5 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in NPAT
CLASSFICATION
Copyright © 2018 Modellab | All Rights Reserved
Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.