CLTC

Summary: Clathrin is a major protein component of the cytoplasmic face of intracellular organelles, called coated vesicles and coated pits. These specialized organelles are involved in the intracellular trafficking of receptors and endocytosis of a variety of macromolecules. The basic subunit of the clathrin coat is composed of three heavy chains and three light chains. [provided by RefSeq, Jul 2008].

Loading, please wait...
Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Nameclathrin heavy chain
OMIM IDMIM:118955
Ensembl IDEnsembl:ENSG00000141367
HGNC IDHGNC:HGNC:2092
PHARMGKB IDPA26618
Map Location17q23.1

Gene Categories:

TUMOR SUPPRESSOR

GO terms in CLTC


Loading, please wait...
Term Type
Evidence Type
GO Term ID
GO Des.
MF HDA GO:0003723 RNA binding
MF IDA GO:0003725 double-stranded RNA binding
MF NAS GO:0005198 structural molecule activity
MF IPI GO:0005515 protein binding
MF ISS GO:0019901 protein kinase binding
MF IBA GO:0030506 ankyrin binding
Showing 1 to 6 of 71 rows rows per page

Gene expression in normal tissue: CLTC

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

undefined37DNA replication2Stilbenoid, diarylheptanoid and gingerol biosynthesis1Mitosis1Ferroptosis1Cell cycle1Genome integrity1Longevity regulating pathway1RTK signaling1p53 pathway1

Pathways in CLTC


Loading, please wait...
Database
Pathway ID
Pathway Des.
reactome R-HSA-1266738 Developmental Biology
reactome R-HSA-1266738 Developmental Biology
reactome R-HSA-1280218 Adaptive Immune System
reactome R-HSA-157858 Gap junction trafficking and regulation
reactome R-HSA-162582 Signal Transduction
reactome R-HSA-162582 Signal Transduction
Showing 1 to 6 of 65 rows rows per page

Gene-Drug: Aster Plot


Loading, please wait...
Drug ID
Drug Name
Model Num.
iGMDRD171 Pemetrexed 3
iGMDRD870 BRD63610 1
iGMDRD187 BRD9876 3
iGMDRD64 Parbendazole 3
Showing 1 to 4 of 50 rows rows per page

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in CLTC

Loading, please wait...
Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

​​​​

SITE
DATATYPES
CLASSFICATION
Map

Copyright © 2018 Modellab | All Rights Reserved

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.