SERPINA2


Summary: This gene encodes a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. The encoded intracellular glycoprotein is localized at the endoplasmic reticulum. This gene is a polymorphic pseudogene, with the non-functional allele being predominant in some populations. Some individuals, as represented by the reference genome allele, contain a 2kb coding region deletion and a start code mutation. [provided by RefSeq, Feb 2014].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
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GO terms in SERPINA2


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Term Type
Evidence Type
GO Term ID
GO Des.
CC IBA GO:0005615 extracellular space
CC IDA GO:0005783 endoplasmic reticulum
BP IBA GO:0010951 negative regulation of endopeptidase activity
BP IEA GO:0010951 negative regulation of endopeptidase activity
MF IBA GO:0004867 serine-type endopeptidase inhibitor activity
MF IPI GO:0005515 protein binding
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Gene expression in normal tissue: SERPINA2

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in SERPINA2


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Database
Pathway ID
Pathway Des.
No matching records found

Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD414 MST-312 3
iGMDRD882 CIL41 2
iGMDRD246 NPC26 2
iGMDRD42 Vorinostat 4
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in SERPINA2

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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