SERPINA2
Summary: This gene encodes a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. The encoded intracellular glycoprotein is localized at the endoplasmic reticulum. This gene is a polymorphic pseudogene, with the non-functional allele being predominant in some populations. Some individuals, as represented by the reference genome allele, contain a 2kb coding region deletion and a start code mutation. [provided by RefSeq, Feb 2014].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
OMIM IDMIM:107410 Ensembl IDEnsembl:ENSG00000258597 HGNC IDHGNC:HGNC:8985 PHARMGKB IDPA35520 Map Location14q32.13 |
GO terms in SERPINA2
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Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
CC | IBA | GO:0005615 | extracellular space |
CC | IDA | GO:0005783 | endoplasmic reticulum |
BP | IBA | GO:0010951 | negative regulation of endopeptidase activity |
BP | IEA | GO:0010951 | negative regulation of endopeptidase activity |
MF | IBA | GO:0004867 | serine-type endopeptidase inhibitor activity |
MF | IPI | GO:0005515 | protein binding |
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Gene expression in normal tissue: SERPINA2
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in SERPINA2
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Database | Pathway ID | Pathway Des. |
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No matching records found |
Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot

Gene-drug targets distribution
Gene Structure: PDB
Models in SERPINA2
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
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No matching records found |