iGMDRD486
| Standard Name | CHEMBL | Pubchem CID | DRUGBANK ID | Drug Status | Drug Type |
|---|---|---|---|---|---|
| Tosedostat | CHEMBL2103847 | 15547700 | DB11781 | Alone | Small Molecule |
Drug Class:
AminesAmino AcidsAmino Acids, Peptides, and ProteinsCarboxylic AcidsHydroxy AcidsHydroxylaminesDrug-model tissue-cancer distribution: Bubble Plot
Drug-gene pathway enrichments
Drug-gene GO enrichments
Drug-Gene: Aster Plot
| Gene ID | Gene Name | Model Num. |
|---|---|---|
| 7514 | XPO1 | 1 |
| 7074 | TIAM1 | 3 |
| 10903 | MTMR11 | 2 |
| 7128 | TNFAIP3 | 2 |
| 8444 | DYRK3 | 3 |
| 2986 | GUCY2F | 3 |
| 4627 | MYH9 | 2 |
| 8289 | ARID1A | 2 |
| 3939 | LDHA | 3 |
| 25778 | DSTYK | 2 |
| 84700 | MYO18B | 1 |
| 9475 | ROCK2 | 1 |
| 6597 | SMARCA4 | 1 |
| 7764 | ZNF217 | 4 |
| 11116 | FGFR1OP | 3 |
| 390502 | SERPINA2 | 3 |
| 56776 | FMN2 | 5 |
| 64783 | RBM15 | 3 |
| 1607 | DGKB | 2 |
| 3694 | ITGB6 | 4 |
| 54822 | TRPM7 | 4 |
| 8844 | KSR1 | 3 |
| 9048 | ARTN | 5 |
| 8295 | TRRAP | 4 |
| 10438 | C1D | 3 |
| 2120 | ETV6 | 1 |
| 9578 | CDC42BPB | 2 |
| 32 | ACACB | 1 |
| 2242 | FES | 1 |
| 2045 | EPHA7 | 3 |
| 1992 | SERPINB1 | 3 |
| 399979 | SNX19 | 1 |
| 23387 | SIK3 | 1 |
| 8859 | STK19 | 1 |
| 7010 | TEK | 1 |
| 5450 | POU2AF1 | 4 |
| 5327 | PLAT | 1 |
| 3236 | HOXD10 | 1 |
| 6794 | STK11 | 4 |
| 10114 | HIPK3 | 1 |
| 84513 | PLPP5 | 3 |
| 4086 | SMAD1 | 1 |
| 5604 | MAP2K1 | 6 |
| 8874 | ARHGEF7 | 4 |
| 1555 | CYP2B6 | 6 |
| 2309 | FOXO3 | 1 |
| 57188 | ADAMTSL3 | 2 |
| 65125 | WNK1 | 2 |
| 5871 | MAP4K2 | 6 |
| 80205 | CHD9 | 1 |
| 8997 | KALRN | 2 |
| 4089 | SMAD4 | 1 |
| 3702 | ITK | 2 |
| 3239 | HOXD13 | 1 |
| 5290 | PIK3CA | 9 |
| 3720 | JARID2 | 2 |
| 64919 | BCL11B | 1 |
| 675 | BRCA2 | 2 |
| 4318 | MMP9 | 3 |
| 11064 | CNTRL | 3 |
| 64750 | SMURF2 | 5 |
| 3308 | HSPA4 | 1 |
| 1459 | CSNK2A2 | 5 |
| 10461 | MERTK | 2 |
| 26278 | SACS | 3 |
| 5747 | PTK2 | 3 |
| 8900 | CCNA1 | 1 |
| 93627 | TBCK | 2 |
| 673 | BRAF | 1 |
| 7153 | TOP2A | 1 |
| 3315 | HSPB1 | 3 |
| 23532 | PRAME | 1 |
| 8924 | HERC2 | 2 |
| 120892 | LRRK2 | 1 |
| 7301 | TYRO3 | 1 |
| 7849 | PAX8 | 4 |
| 9451 | EIF2AK3 | 2 |
| 57521 | RPTOR | 3 |
| 23281 | MTUS2 | 2 |
| 2324 | FLT4 | 2 |
| 23090 | ZNF423 | 1 |
| 5582 | PRKCG | 4 |
| 2119 | ETV5 | 1 |
| 2046 | EPHA8 | 2 |
| 5927 | KDM5A | 2 |
| 57448 | BIRC6 | 3 |
| 2157 | F8 | 1 |
| 7227 | TRPS1 | 3 |
| 3709 | ITPR2 | 1 |
| 6778 | STAT6 | 3 |
| 8428 | STK24 | 1 |
| 182 | JAG1 | 3 |
| 51167 | CYB5R4 | 8 |
| 8661 | EIF3A | 3 |
| 7403 | KDM6A | 1 |
| 4638 | MYLK | 2 |
| 4205 | MEF2A | 3 |
| 7040 | TGFB1 | 2 |
| 57697 | FANCM | 1 |
| 440270 | GOLGA8B | 1 |
| 4629 | MYH11 | 3 |
| 4486 | MST1R | 1 |
Gene in drug-gene network: Network Plot
Models in Tosedostat
CLASSFICATION
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Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.