ETV5
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| ETS variant 5 | MIM:601600 | Ensembl:ENSG00000244405 | HGNC:HGNC:3494 | PA27908 | 3q27.2 |
Gene Categories:
CLINICALLY ACTIONABLEGO terms in ETV5
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | IBA | GO:0005634 | nucleus |
| CC | IDA | GO:0005634 | nucleus |
| CC | IDA | GO:0005654 | nucleoplasm |
| CC | IEA | GO:0005886 | plasma membrane |
| BP | IBA | GO:0006357 | regulation of transcription by RNA polymerase II |
| BP | IEA | GO:0006366 | transcription by RNA polymerase II |
| BP | IEA | GO:0007274 | neuromuscular synaptic transmission |
| BP | IEA | GO:0007626 | locomotory behavior |
| BP | IBA | GO:0030154 | cell differentiation |
| BP | IDA | GO:0034599 | cellular response to oxidative stress |
| BP | IEA | GO:0045666 | positive regulation of neuron differentiation |
| BP | IMP | GO:0045944 | positive regulation of transcription by RNA polymerase II |
| BP | IEA | GO:0048133 | male germ-line stem cell asymmetric division |
| BP | IEA | GO:0050807 | regulation of synapse organization |
| BP | IEA | GO:0060252 | positive regulation of glial cell proliferation |
| BP | IEA | GO:0060762 | regulation of branching involved in mammary gland duct morphogenesis |
| BP | IEA | GO:0071340 | skeletal muscle acetylcholine-gated channel clustering |
| MF | IMP | GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding |
| MF | IBA | GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding |
| MF | ISA | GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding |
| MF | IMP | GO:0001228 | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding |
| MF | TAS | GO:0003677 | DNA binding |
| MF | IDA | GO:0003700 | DNA-binding transcription factor activity |
| MF | IPI | GO:0005515 | protein binding |
| MF | IDA | GO:0044212 | transcription regulatory region DNA binding |
Gene expression in normal tissue: ETV5
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in ETV5
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| biocarta | il12pathway | il12 and stat4 dependent signaling pathway in th1 development |
| wikipathways | WP138 | Androgen receptor signaling pathway |
| kegg | hsa05202 | Transcriptional misregulation in cancer - Homo sapiens (human) |
| kegg | hsa05215 | Prostate cancer - Homo sapiens (human) |
| pid | foxm1pathway | FOXM1 transcription factor network |
| pid | il12_stat4pathway | IL12 signaling mediated by STAT4 |
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD427 | ABT737 | 6 |
| iGMDRD144 | NSC95397 | 3 |
| iGMDRD318 | PAC-1 | 6 |
| iGMDRD885 | Compound 110 | 3 |
| iGMDRD486 | Tosedostat | 1 |
| iGMDRD387 | CHIR-99021 | 3 |
| iGMDRD889 | Compound 7d-cis | 6 |
| iGMDRD420 | Leucascandrolide A | 6 |
| iGMDRD300 | Tozasertib | 6 |
| iGMDRD280 | CYTOCHALASIN B | 6 |
| iGMDRD353 | PD0325901 | 2 |
| iGMDRD435 | BI-2536 | 6 |
| iGMDRD446 | LY 2183240 | 6 |
| iGMDRD286 | Nsc 632839 | 3 |
| iGMDRD562 | Navitoclax | 6 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in ETV5
CLASSFICATION
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