STK19
Summary: This gene encodes a serine/threonine kinase which localizes predominantly to the nucleus. Its specific function is unknown; it is possible that phosphorylation of this protein is involved in transcriptional regulation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6 and expresses two transcript variants. [provided by RefSeq, Jul 2008].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| serine/threonine kinase 19 | MIM:604977 | Ensembl:ENSG00000204344 | HGNC:HGNC:11398 | PA36206 | 6p21.33 |
GO terms in STK19
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IEA | GO:0004674 | protein serine/threonine kinase activity |
| MF | IEA | GO:0005524 | ATP binding |
| CC | TAS | GO:0005634 | nucleus |
| CC | IDA | GO:0016607 | nuclear speck |
| BP | TAS | GO:0006468 | protein phosphorylation |
Gene expression in normal tissue: STK19
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in STK19
| Database | Pathway ID | Pathway Des. |
|---|
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD60 | Quinoclamine | 3 |
| iGMDRD506 | Fedratinib | 3 |
| iGMDRD577 | BIX01294 | 3 |
| iGMDRD398 | Sepantronium | 2 |
| iGMDRD562 | Navitoclax | 7 |
| iGMDRD100 | Zebularine | 2 |
| iGMDRD318 | PAC-1 | 2 |
| iGMDRD187 | BRD9876 | 1 |
| iGMDRD513 | BML-259 | 1 |
| iGMDRD394 | BX-795 | 1 |
| iGMDRD201 | SKI II | 2 |
| iGMDRD483 | SCH-529074 | 3 |
| iGMDRD144 | NSC95397 | 6 |
| iGMDRD599 | Salermide | 3 |
| iGMDRD1008 | SR-II-138A | 6 |
| iGMDRD579 | PF750 | 3 |
| iGMDRD420 | Leucascandrolide A | 3 |
| iGMDRD263 | AACOCF3 | 3 |
| iGMDRD367 | Ro 28-1675 | 3 |
| iGMDRD872 | BRD7137 | 3 |
| iGMDRD77 | Itraconazole | 3 |
| iGMDRD6 | AM-580 | 3 |
| iGMDRD434 | BMS-536924 | 3 |
| iGMDRD5 | Tyrphostin AG 1478 | 3 |
| iGMDRD220 | fumonisin B1 | 3 |
| iGMDRD158 | NSC141540 | 1 |
| iGMDRD202 | Curcumin | 1 |
| iGMDRD883 | CIL55A | 1 |
| iGMDRD945 | ML214 | 3 |
| iGMDRD698 | Neratinib | 6 |
| iGMDRD499 | PDMP | 3 |
| iGMDRD701 | NVP-AUY922 | 1 |
| iGMDRD583 | LDN 193189 | 5 |
| iGMDRD560 | MK-2206 | 3 |
| iGMDRD486 | Tosedostat | 1 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in STK19
CLASSFICATION
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