RBM15

Summary: Members of the SPEN (Split-end) family of proteins, including RBM15, have repressor function in several signaling pathways and may bind to RNA through interaction with spliceosome components (Hiriart et al., 2005 [PubMed 16129689]).[supplied by OMIM, Feb 2009].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
NameRNA binding motif protein 15
OMIM IDMIM:606077
Ensembl IDEnsembl:ENSG00000162775
HGNC IDHGNC:HGNC:14959
PHARMGKB IDPA34264
Map Location1p13.3

GO terms in RBM15


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Term Type
Evidence Type
GO Term ID
GO Des.
CC IBA GO:0005634 nucleus
CC IDA GO:0005654 nucleoplasm
CC IDA GO:0016607 nuclear speck
CC IEA GO:0031965 nuclear membrane
CC IDA GO:0036396 RNA N6-methyladenosine methyltransferase complex
BP IDA GO:0000381 regulation of alternative mRNA splicing, via spliceosome
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Gene expression in normal tissue: RBM15

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

undefined42Apoptosis regulation2ERK MAPK signaling2Chromatin histone acetylation2PI3K/MTOR signaling2One carbon pool by folate1p53 pathway1Proteasome1Leukocyte transendothelial migration1Mitosis1

Pathways in RBM15


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Database
Pathway ID
Pathway Des.
No matching records found

Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD286 Nsc 632839 4
iGMDRD871 BRD6368 2
iGMDRD366 PI-103 2
iGMDRD505 Pevonedistat 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in RBM15

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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