RBM15


Summary: Members of the SPEN (Split-end) family of proteins, including RBM15, have repressor function in several signaling pathways and may bind to RNA through interaction with spliceosome components (Hiriart et al., 2005 [PubMed 16129689]).[supplied by OMIM, Feb 2009].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
RNA binding motif protein 15MIM:606077Ensembl:ENSG00000162775HGNC:HGNC:14959PA342641p13.3

GO terms in RBM15


Term TypeEvidence TypeGO Term IDGO Des.
CCIBAGO:0005634nucleus
CCIDAGO:0005654nucleoplasm
CCIDAGO:0016607nuclear speck
CCIEAGO:0031965nuclear membrane
CCIDAGO:0036396RNA N6-methyladenosine methyltransferase complex
BPIDAGO:0000381regulation of alternative mRNA splicing, via spliceosome
BPIBAGO:0000398mRNA splicing, via spliceosome
BPIDAGO:0001510RNA methylation
BPIEAGO:0001569branching involved in blood vessel morphogenesis
BPIEAGO:0007221positive regulation of transcription of Notch receptor target
BPIDAGO:0009048dosage compensation by inactivation of X chromosome
BPIEAGO:0016032viral process
BPISSGO:0038163thrombopoietin-mediated signaling pathway
BPIEAGO:0045638negative regulation of myeloid cell differentiation
BPIDAGO:0045652regulation of megakaryocyte differentiation
BPIDAGO:0045892negative regulation of transcription, DNA-templated
BPIEAGO:0048536spleen development
BPIEAGO:0060412ventricular septum morphogenesis
BPIEAGO:0060674placenta blood vessel development
MFIBAGO:0003676nucleic acid binding
MFHDAGO:0003723RNA binding
MFIDAGO:0003723RNA binding
MFIDAGO:0003729mRNA binding
MFIPIGO:0005515protein binding

Gene expression in normal tissue: RBM15

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in RBM15


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD286Nsc 6328394
iGMDRD871BRD63682
iGMDRD366PI-1032
iGMDRD505Pevonedistat1
iGMDRD246NPC262
iGMDRD42Vorinostat1
iGMDRD353PD03259011
iGMDRD322FK 8662
iGMDRD990PL.DI1
iGMDRD121GMX17783
iGMDRD208Necrosulfonamide1
iGMDRD137Indisulam3
iGMDRD289Parthenolide2
iGMDRD864BRD-K990069451
iGMDRD705Nakiterpiosin5
iGMDRD267Oligomycin A6
iGMDRD57Chloropentafluorobenzene4
iGMDRD314Tanespimycin3
iGMDRD351GW843682X6
iGMDRD123Isoevodiamine4
iGMDRD176Decitabine1
iGMDRD84Lovastatin acid3
iGMDRD486Tosedostat3
iGMDRD584VER 1550082
iGMDRD560MK-22062
iGMDRD681SB-7439211
iGMDRD50Cytarabine1
iGMDRD79Gemcitabine2
iGMDRD188Piperlongumine5
iGMDRD100Zebularine4
iGMDRD730Kahalalide F2
iGMDRD74Idarubicin1
iGMDRD399Selumetinib3
iGMDRD851BRD-K342228891
iGMDRD562Navitoclax2
iGMDRD398Sepantronium4
iGMDRD60Quinoclamine2
iGMDRD64Parbendazole4
iGMDRD356PNU-746543
iGMDRD451Serdemetan1
iGMDRD138PX 124
iGMDRD852BRD-K356044181
iGMDRD255SB2250022
iGMDRD260FQI-24
iGMDRD171Pemetrexed3
iGMDRD117Docetaxel1
iGMDRD294Batimastat1
iGMDRD446LY 21832401
iGMDRD193Fqi13
iGMDRD152179324-69-77
iGMDRD61Kinetin riboside2
iGMDRD280CYTOCHALASIN B2
iGMDRD466Chaetocin6
iGMDRD126Tipifarnib9
iGMDRD151CHM-16
iGMDRD554CHEMBL14341372
iGMDRD599Salermide1
iGMDRD1008SR-II-138A1
iGMDRD779PRL-3 Inhibitor I2
iGMDRD483SCH-5290743
iGMDRD494Neopeltolide2

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in RBM15

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