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iGMDRD176

Canonical SMILES: C1C(C(OC1N2C=NC(=NC2=O)N)CO)O

InChI: InChI=1S/C8H12N4O4/c9-7-10-3-12(8(15)11-7)6-1-4(14)5(2-13)16-6/h3-6,13-14H,1-2H2,(H2,9,11,15)/t4-,5+,6+/m0/s1

InChI Key: XAUDJQYHKZQPEU-KVQBGUIXSA-N

Standard Name	CHEMBL	Pubchem CID	KEGG Drug ID	DRUGBANK ID	Drug Status	Drug targets (TTD)	Drug Type
Decitabine	CHEMBL1201129	451668	D03665	DB01262	Alone	DAP000641	Small Molecule

Drug Class:

Antimetabolites Antimetabolites, Antineoplastic Antineoplastic Agents Antineoplastic and Immunomodulating Agents Aza Compounds Carbohydrates Cytidine DNA Modification Methylases, antagonists & inhibitors Enzyme Inhibitors Glycosides Heterocyclic Compounds Heterocyclic Compounds, 1-Ring Immunosuppressive Agents Myelodysplastic Syndromes Myelosuppressive Agents Noxae Nucleic Acids, Nucleotides, and Nucleosides Nucleoside Metabolic Inhibitor Nucleosides Pyrimidine Analogues Pyrimidine Nucleosides Pyrimidines Ribonucleosides Teratogens Toxic Actions

Drug Targets:

DNA DNMT1 (P26358)

Drug Pathways:

Cysteine and methionine metabolism MicroRNAs in cancer

Drug Synonyms:

Decitabine (USAN/INN)Dacogen (TN)

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot

Gene ID	Gene Name	Model Num.
7514	XPO1	1
3845	KRAS	3
64783	RBM15	1
1786	DNMT1	1
7037	TFRC	1
3667	IRS1	1
7157	TP53	4
4086	SMAD1	1
1788	DNMT3A	1
100862685	ERVK-19	1
4893	NRAS	1
94	ACVRL1	1
1803	DPP4	1

Gene in drug-gene network: Network Plot

Models in Decitabine

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