iGMDRD852

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Standard Name
Drug Status
Standard NameBRD-K35604418
Drug StatusAlone

Drug Targets:

MCL1

Drug-model tissue-cancer distribution: Bubble Plot

LUNtissue: LUN cancer: LUNG model num: 0LUNGtissue: LUNG cancer: undefined model num: 1undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 8

Drug-gene pathway enrichments

7reactome: Signal Transduction4reactome: Signaling by Receptor Tyrosine Kinases3reactome: Disease2reactome: Signaling by TGF-beta family members2wikipathways: Focal Adhesion2kegg: MAPK signaling pathway - Homo sapiens (human)2pharmgkb: Pathway_PA1659594252wikipathways: Angiogenesis2kegg: Focal adhesion - Homo sapiens (human)2kegg: Proteoglycans in cancer - Homo sapiens (human)

Drug-gene GO enrichments

9CC: nucleus6CC: cytosol5MF: protein binding5CC: cytoplasm5CC: plasma membrane4BP: BMP signaling pathway3MF: RNA binding3MF: protein tyrosine kinase activity3CC: integral component of plasma membrane3BP: positive regulation of ERK1 and ERK2 cascade

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
7514 XPO1 1
64783 RBM15 1
3791 KDR 1
4086 SMAD1 1
Showing 1 to 4 of 6 rows

Gene in drug-gene network: Network Plot

Models in BRD-K35604418

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
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