ADAMTSL3
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| ADAMTS like 3 | MIM:609199 | Ensembl:ENSG00000156218 | HGNC:HGNC:14633 | PA134934525 | 15q25.2 |
GO terms in ADAMTSL3
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IPI | GO:0005515 | protein binding |
| MF | IEA | GO:0008233 | peptidase activity |
| CC | IEA | GO:0005576 | extracellular region |
| CC | IDA | GO:0043231 | intracellular membrane-bounded organelle |
| BP | IEA | GO:0006508 | proteolysis |
Gene expression in normal tissue: ADAMTSL3
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in ADAMTSL3
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-1643685 | Disease |
| reactome | R-HSA-3781865 | Diseases of glycosylation |
| reactome | R-HSA-3906995 | Diseases associated with O-glycosylation of proteins |
| reactome | R-HSA-392499 | Metabolism of proteins |
| reactome | R-HSA-5083635 | Defective B3GALTL causes Peters-plus syndrome (PpS) |
| reactome | R-HSA-5173105 | O-linked glycosylation |
| reactome | R-HSA-5173214 | O-glycosylation of TSR domain-containing proteins |
| reactome | R-HSA-597592 | Post-translational protein modification |
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD289 | Parthenolide | 1 |
| iGMDRD77 | Itraconazole | 2 |
| iGMDRD481 | Dactolisib | 6 |
| iGMDRD271 | Brefeldin A | 6 |
| iGMDRD202 | Curcumin | 1 |
| iGMDRD5 | Tyrphostin AG 1478 | 2 |
| iGMDRD552 | AZD-1775 | 1 |
| iGMDRD263 | AACOCF3 | 1 |
| iGMDRD505 | Pevonedistat | 1 |
| iGMDRD886 | Compound 1541A | 1 |
| iGMDRD871 | BRD6368 | 2 |
| iGMDRD414 | MST-312 | 2 |
| iGMDRD286 | Nsc 632839 | 2 |
| iGMDRD366 | PI-103 | 3 |
| iGMDRD329 | Merck60 | 2 |
| iGMDRD424 | Tamatinib | 3 |
| iGMDRD150 | RITA | 1 |
| iGMDRD560 | MK-2206 | 5 |
| iGMDRD330 | BRD4132 | 4 |
| iGMDRD486 | Tosedostat | 2 |
| iGMDRD341 | Triacsin c | 5 |
| iGMDRD782 | DC-45-A2 | 2 |
| iGMDRD52 | Rotenone | 2 |
| iGMDRD885 | Compound 110 | 9 |
| iGMDRD474 | Avrainvillamide | 3 |
| iGMDRD255 | SB225002 | 2 |
| iGMDRD369 | TGX-115 | 5 |
| iGMDRD131 | Erlotinib | 1 |
| iGMDRD524 | ISX-9 | 3 |
| iGMDRD23 | Gossypol | 1 |
| iGMDRD780 | PP-30 | 3 |
| iGMDRD506 | Fedratinib | 1 |
| iGMDRD577 | BIX01294 | 1 |
| iGMDRD888 | Compound 44 | 3 |
| iGMDRD779 | PRL-3 Inhibitor I | 2 |
| iGMDRD144 | NSC95397 | 2 |
| iGMDRD484 | Pluripotin | 3 |
| iGMDRD494 | Neopeltolide | 1 |
| iGMDRD554 | CHEMBL1434137 | 1 |
| iGMDRD889 | Compound 7d-cis | 1 |
| iGMDRD394 | BX-795 | 1 |
| iGMDRD280 | CYTOCHALASIN B | 7 |
| iGMDRD679 | Bistramide A | 2 |
| iGMDRD634 | SCHEMBL2608041 | 2 |
| iGMDRD159 | 3-Chloro-L-alanine | 1 |
| iGMDRD359 | OSW-1 | 4 |
| iGMDRD446 | LY 2183240 | 2 |
| iGMDRD152 | 179324-69-7 | 2 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in ADAMTSL3
CLASSFICATION
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