HIPK3
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| homeodomain interacting protein kinase 3 | MIM:604424 | Ensembl:ENSG00000110422 | HGNC:HGNC:4915 | PA29292 | 11p13 |
GO terms in HIPK3
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IDA | GO:0004672 | protein kinase activity |
| MF | IDA | GO:0004674 | protein serine/threonine kinase activity |
| MF | ISS | GO:0004674 | protein serine/threonine kinase activity |
| MF | IEA | GO:0005524 | ATP binding |
| CC | IDA | GO:0005829 | cytosol |
| CC | IDA | GO:0016604 | nuclear body |
| CC | IEA | GO:0016605 | PML body |
| BP | IEA | GO:0006355 | regulation of transcription, DNA-templated |
| BP | IDA | GO:0006468 | protein phosphorylation |
| BP | IEA | GO:0006915 | apoptotic process |
| BP | IDA | GO:0009299 | mRNA transcription |
| BP | ISS | GO:0018105 | peptidyl-serine phosphorylation |
| BP | ISS | GO:0018107 | peptidyl-threonine phosphorylation |
| BP | IMP | GO:0043066 | negative regulation of apoptotic process |
| BP | ISS | GO:0043508 | negative regulation of JUN kinase activity |
Gene expression in normal tissue: HIPK3
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in HIPK3
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| wikipathways | WP2001 | miR-targeted genes in adipocytes - TarBase |
| wikipathways | WP2004 | miR-targeted genes in lymphocytes - TarBase |
| wikipathways | WP2005 | miR-targeted genes in muscle cell - TarBase |
| netpath | Pathway_EGFR1 | EGFR1 |
| kegg | hsa04218 | Cellular senescence - Homo sapiens (human) |
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD414 | MST-312 | 3 |
| iGMDRD506 | Fedratinib | 3 |
| iGMDRD369 | TGX-115 | 3 |
| iGMDRD300 | Tozasertib | 3 |
| iGMDRD886 | Compound 1541A | 3 |
| iGMDRD802 | 4-methylfasudil | 3 |
| iGMDRD434 | BMS-536924 | 3 |
| iGMDRD267 | Oligomycin A | 3 |
| iGMDRD885 | Compound 110 | 1 |
| iGMDRD446 | LY 2183240 | 2 |
| iGMDRD152 | 179324-69-7 | 3 |
| iGMDRD394 | BX-795 | 3 |
| iGMDRD280 | CYTOCHALASIN B | 3 |
| iGMDRD123 | Isoevodiamine | 5 |
| iGMDRD435 | BI-2536 | 4 |
| iGMDRD154 | NSC23766 | 1 |
| iGMDRD634 | SCHEMBL2608041 | 11 |
| iGMDRD486 | Tosedostat | 1 |
| iGMDRD420 | Leucascandrolide A | 2 |
| iGMDRD512 | nutlin 3 | 4 |
| iGMDRD150 | RITA | 2 |
| iGMDRD781 | Sirolimus | 3 |
| iGMDRD523 | Cyanoquinoline, 11 | 2 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in HIPK3
CLASSFICATION
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