KSR1

Summary:

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Namekinase suppressor of ras 1
OMIM IDMIM:601132
Ensembl IDEnsembl:ENSG00000141068
HGNC IDHGNC:HGNC:6465
PHARMGKB IDPA30254
Map Location17q11.2

GO terms in KSR1


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Term Type
Evidence Type
GO Term ID
GO Des.
MF NAS GO:0004672 protein kinase activity
MF ISS GO:0005078 MAP-kinase scaffold activity
MF IPI GO:0005515 protein binding
MF IEA GO:0005524 ATP binding
MF IDA GO:0008022 protein C-terminus binding
MF IEA GO:0031434 mitogen-activated protein kinase kinase binding
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Gene expression in normal tissue: KSR1

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

undefined11Apoptosis regulation2Other, kinases1Mitosis1Cell cycle1Longevity regulating pathway1

Pathways in KSR1


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Database
Pathway ID
Pathway Des.
reactome R-HSA-162582 Signal Transduction
reactome R-HSA-1643685 Disease
reactome R-HSA-5663202 Diseases of signal transduction
reactome R-HSA-5673000 RAF activation
reactome R-HSA-5673001 RAF/MAP kinase cascade
reactome R-HSA-5674135 MAP2K and MAPK activation
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD427 ABT737 6
iGMDRD781 Sirolimus 4
iGMDRD486 Tosedostat 3
iGMDRD889 Compound 7d-cis 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in KSR1

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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