iGMDRD686


Canonical SMILES: CCC1=CN=CN=C1N2CCN(CC2)CC3=NC4=C(N3)C=C(C=C4)C(F)(F)F

InChI: InChI=1S/C19H21F3N6/c1-2-13-10-23-12-24-18(13)28-7-5-27(6-8-28)11-17-25-15-4-3-14(19(20,21)22)9-16(15)26-17/h3-4,9-10,12H,2,5-8,11H2,1H3,(H,25,26)

InChI Key: FBLPQCAQRNSVHB-UHFFFAOYSA-N

Loading, please wait...
Standard Name
Pubchem CID
Drug Status
Drug Type
Standard NamePF4708671
Pubchem CID51371300
Drug StatusAlone
Drug TypeSmall Molecule

Drug Targets:

RPS6KB1 (p70S6KA)

Drug Pathways:

PI3K/MTOR signaling

Drug-model tissue-cancer distribution: Bubble Plot

BREAStissue: BREAS cancer: BREAST model num: 0BREASTtissue: BREAST cancer: undefined model num: 1BREASTtissue: BREAST cancer: Breast Carcinoma model num: 1undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 5SKItissue: SKI cancer: SKIN model num: 0SKINtissue: SKIN cancer: undefined model num: 1SKINtissue: SKIN cancer: Cutaneous Melanoma (SKCM) model num: 1LUNtissue: LUN cancer: LUNG model num: 0LUNGtissue: LUNG cancer: Lung Adenocarcinoma (LUAD) model num: 1STOMACtissue: STOMAC cancer: STOMACH model num: 0STOMACHtissue: STOMACH cancer: Stomach Adenocarcinoma (STAD) model num: 1

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


Loading, please wait...
Gene ID
Gene Name
Model Num.
6597 SMARCA4 1
390502 SERPINA2 1
5079 PAX5 1
84337 ELOF1 1
Showing 1 to 4 of 16 rows rows per page

Gene in drug-gene network: Network Plot

Models in PF4708671

Loading, please wait...
Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

​​​​