iGMDRD594

Canonical SMILES: CC1COCCN1C2=NC(=NC3=C2C=CC(=N3)C4=CC(=C(C=C4)OC)CO)N5CCOCC5C

InChI: InChI=1S/C25H31N5O4/c1-16-14-33-10-8-29(16)24-20-5-6-21(18-4-7-22(32-3)19(12-18)13-31)26-23(20)27-25(28-24)30-9-11-34-15-17(30)2/h4-7,12,16-17,31H,8-11,13-15H2,1-3H3/t16-,17-/m0/s1

InChI Key: KVLFRAWTRWDEDF-IRXDYDNUSA-N

Standard NameCHEMBLPubchem CIDDRUGBANK IDDrug StatusDrug Type
AZD-8055CHEMBL1801204 25263000DB12774AloneSmall Molecule


Drug Targets:

MTORC1/2

Drug Pathways:

PI3K/MTOR signaling

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


Gene IDGene NameModel Num.
2475MTOR2
390502SERPINA21
29126CD2741
11200CHEK21
29904EEF2K1
10413YAP11
7157TP531
27086FOXP11
3791KDR1
2071ERCC31
57111RAB251
4089SMAD41
1956EGFR1
5315PKM1
26278SACS1
3553IL1B1
7301TYRO31
7385UQCRC21
100862685ERVK-191
4893NRAS1
2065ERBB31
54790TET21
4613MYCN1
3265HRAS1
5624PROC1

Gene in drug-gene network: Network Plot

Models in AZD-8055

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