MTOR
Summary: The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq, Sep 2008].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| mechanistic target of rapamycin kinase | MIM:601231 | Ensembl:ENSG00000198793 | HGNC:HGNC:3942 | PA28360 | 1p36.22 |
GO terms in MTOR
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IDA | GO:0001558 | regulation of cell growth |
| BP | IEA | GO:0001933 | negative regulation of protein phosphorylation |
| BP | IDA | GO:0001934 | positive regulation of protein phosphorylation |
| BP | IEA | GO:0001938 | positive regulation of endothelial cell proliferation |
| BP | IEA | GO:0003007 | heart morphogenesis |
| BP | IEA | GO:0003179 | heart valve morphogenesis |
| BP | IEA | GO:0005979 | regulation of glycogen biosynthetic process |
| BP | IEA | GO:0006112 | energy reserve metabolic process |
| BP | IEA | GO:0006207 | 'de novo' pyrimidine nucleobase biosynthetic process |
| BP | IBA | GO:0006281 | DNA repair |
| BP | IDA | GO:0006468 | protein phosphorylation |
| BP | IMP | GO:0006468 | protein phosphorylation |
| BP | TAS | GO:0007050 | cell cycle arrest |
| BP | IEA | GO:0007281 | germ cell development |
| BP | IEA | GO:0007420 | brain development |
| BP | IEA | GO:0007569 | cell aging |
| BP | IMP | GO:0007584 | response to nutrient |
| BP | IEA | GO:0007616 | long-term memory |
| BP | IMP | GO:0008361 | regulation of cell size |
| BP | IEA | GO:0008542 | visual learning |
| BP | IDA | GO:0009267 | cellular response to starvation |
| BP | IEA | GO:0009791 | post-embryonic development |
| BP | IMP | GO:0010507 | negative regulation of autophagy |
| BP | ISS | GO:0010507 | negative regulation of autophagy |
| BP | IEA | GO:0010592 | positive regulation of lamellipodium assembly |
| BP | IMP | GO:0010628 | positive regulation of gene expression |
| BP | IMP | GO:0010718 | positive regulation of epithelial to mesenchymal transition |
| BP | IEA | GO:0010831 | positive regulation of myotube differentiation |
| BP | IEA | GO:0014042 | positive regulation of neuron maturation |
| BP | IEA | GO:0014736 | negative regulation of muscle atrophy |
| BP | IEA | GO:0014823 | response to activity |
| BP | TAS | GO:0016241 | regulation of macroautophagy |
| BP | IDA | GO:0016242 | negative regulation of macroautophagy |
| BP | IDA | GO:0016310 | phosphorylation |
| BP | IMP | GO:0018105 | peptidyl-serine phosphorylation |
| BP | IEA | GO:0018107 | peptidyl-threonine phosphorylation |
| BP | IEA | GO:0021510 | spinal cord development |
| BP | TAS | GO:0030163 | protein catabolic process |
| BP | IEA | GO:0030838 | positive regulation of actin filament polymerization |
| BP | IEA | GO:0031397 | negative regulation of protein ubiquitination |
| BP | IEA | GO:0031529 | ruffle organization |
| BP | IEA | GO:0031641 | regulation of myelination |
| BP | ISS | GO:0031669 | cellular response to nutrient levels |
| BP | IMP | GO:0031929 | TOR signaling |
| BP | NAS | GO:0031929 | TOR signaling |
| BP | IEA | GO:0031998 | regulation of fatty acid beta-oxidation |
| BP | IEA | GO:0032095 | regulation of response to food |
| BP | TAS | GO:0032148 | activation of protein kinase B activity |
| BP | TAS | GO:0032516 | positive regulation of phosphoprotein phosphatase activity |
| BP | IEA | GO:0032868 | response to insulin |
| BP | IMP | GO:0032956 | regulation of actin cytoskeleton organization |
| BP | IDA | GO:0034198 | cellular response to amino acid starvation |
| BP | IEA | GO:0035176 | social behavior |
| BP | IEA | GO:0035264 | multicellular organism growth |
| BP | IDA | GO:0038202 | TORC1 signaling |
| BP | IMP | GO:0038202 | TORC1 signaling |
| BP | IEA | GO:0042060 | wound healing |
| BP | IEA | GO:0042220 | response to cocaine |
| BP | IEA | GO:0043087 | regulation of GTPase activity |
| BP | IDA | GO:0043200 | response to amino acid |
| BP | NAS | GO:0043276 | anoikis |
| BP | IEA | GO:0043278 | response to morphine |
| BP | IEA | GO:0043610 | regulation of carbohydrate utilization |
| BP | IEA | GO:0045429 | positive regulation of nitric oxide biosynthetic process |
| BP | ISS | GO:0045670 | regulation of osteoclast differentiation |
| BP | IDA | GO:0045727 | positive regulation of translation |
| BP | IEA | GO:0045792 | negative regulation of cell size |
| BP | IMP | GO:0045945 | positive regulation of transcription by RNA polymerase III |
| BP | IDA | GO:0046777 | protein autophosphorylation |
| BP | IMP | GO:0046889 | positive regulation of lipid biosynthetic process |
| BP | IEA | GO:0048255 | mRNA stabilization |
| BP | IEA | GO:0048661 | positive regulation of smooth muscle cell proliferation |
| BP | IEA | GO:0048714 | positive regulation of oligodendrocyte differentiation |
| BP | IEA | GO:0050731 | positive regulation of peptidyl-tyrosine phosphorylation |
| BP | IEA | GO:0050882 | voluntary musculoskeletal movement |
| BP | IEA | GO:0051496 | positive regulation of stress fiber assembly |
| BP | IMP | GO:0051549 | positive regulation of keratinocyte migration |
| BP | IEA | GO:0051897 | positive regulation of protein kinase B signaling |
| BP | IEA | GO:0055013 | cardiac muscle cell development |
| BP | IEA | GO:0060048 | cardiac muscle contraction |
| BP | IEA | GO:0060135 | maternal process involved in female pregnancy |
| BP | IEA | GO:0060252 | positive regulation of glial cell proliferation |
| BP | IEA | GO:0060999 | positive regulation of dendritic spine development |
| BP | IEA | GO:0061051 | positive regulation of cell growth involved in cardiac muscle cell development |
| BP | IEA | GO:0070885 | negative regulation of calcineurin-NFAT signaling cascade |
| BP | IDA | GO:0071230 | cellular response to amino acid stimulus |
| BP | IDA | GO:0071233 | cellular response to leucine |
| BP | ISS | GO:0071456 | cellular response to hypoxia |
| BP | IEA | GO:0090335 | regulation of brown fat cell differentiation |
| BP | IEA | GO:0090559 | regulation of membrane permeability |
| BP | TAS | GO:1900034 | regulation of cellular response to heat |
| BP | IEA | GO:1901216 | positive regulation of neuron death |
| BP | IMP | GO:1901838 | positive regulation of transcription of nucleolar large rRNA by RNA polymerase I |
| BP | IMP | GO:1903691 | positive regulation of wound healing, spreading of epidermal cells |
| BP | IEA | GO:1904000 | positive regulation of eating behavior |
| BP | IEA | GO:1904056 | positive regulation of cholangiocyte proliferation |
| BP | IEA | GO:1904058 | positive regulation of sensory perception of pain |
| BP | IEA | GO:1904193 | negative regulation of cholangiocyte apoptotic process |
| BP | IEA | GO:1904197 | positive regulation of granulosa cell proliferation |
| BP | IEA | GO:1904206 | positive regulation of skeletal muscle hypertrophy |
| BP | IEA | GO:1904213 | negative regulation of iodide transmembrane transport |
| BP | TAS | GO:1904690 | positive regulation of cytoplasmic translational initiation |
| BP | IDA | GO:1990253 | cellular response to leucine starvation |
| CC | IEA | GO:0000139 | Golgi membrane |
| CC | IBA | GO:0005634 | nucleus |
| CC | TAS | GO:0005654 | nucleoplasm |
| CC | IDA | GO:0005737 | cytoplasm |
| CC | IEA | GO:0005741 | mitochondrial outer membrane |
| CC | IDA | GO:0005764 | lysosome |
| CC | IMP | GO:0005764 | lysosome |
| CC | HDA | GO:0005765 | lysosomal membrane |
| CC | IEA | GO:0005789 | endoplasmic reticulum membrane |
| CC | TAS | GO:0005829 | cytosol |
| CC | IDA | GO:0012505 | endomembrane system |
| CC | HDA | GO:0016020 | membrane |
| CC | IDA | GO:0016020 | membrane |
| CC | ISS | GO:0016605 | PML body |
| CC | IEA | GO:0030425 | dendrite |
| CC | IDA | GO:0031931 | TORC1 complex |
| CC | IMP | GO:0031931 | TORC1 complex |
| CC | IDA | GO:0031932 | TORC2 complex |
| CC | IEA | GO:0043025 | neuronal cell body |
| MF | IDA | GO:0001030 | RNA polymerase III type 1 promoter DNA binding |
| MF | IDA | GO:0001031 | RNA polymerase III type 2 promoter DNA binding |
| MF | IDA | GO:0001032 | RNA polymerase III type 3 promoter DNA binding |
| MF | IDA | GO:0001156 | TFIIIC-class transcription factor binding |
| MF | IDA | GO:0004672 | protein kinase activity |
| MF | EXP | GO:0004674 | protein serine/threonine kinase activity |
| MF | IDA | GO:0004674 | protein serine/threonine kinase activity |
| MF | TAS | GO:0004674 | protein serine/threonine kinase activity |
| MF | IPI | GO:0005515 | protein binding |
| MF | IEA | GO:0005524 | ATP binding |
| MF | IBA | GO:0016301 | kinase activity |
| MF | IDA | GO:0016301 | kinase activity |
| MF | TAS | GO:0016301 | kinase activity |
| MF | IEA | GO:0019901 | protein kinase binding |
| MF | IEA | GO:0019904 | protein domain specific binding |
| MF | IPI | GO:0042802 | identical protein binding |
| MF | IEA | GO:0043022 | ribosome binding |
| MF | IPI | GO:0051219 | phosphoprotein binding |
Gene expression in normal tissue: MTOR
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in MTOR
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| wikipathways | WP1403 | AMP-activated Protein Kinase (AMPK) Signaling |
| wikipathways | WP1471 | Target Of Rapamycin (TOR) Signaling |
| wikipathways | WP1544 | MicroRNAs in cardiomyocyte hypertrophy |
| wikipathways | WP1584 | Type II diabetes mellitus |
| wikipathways | WP1982 | Sterol Regulatory Element-Binding Proteins (SREBP) signalling |
| wikipathways | WP1984 | Integrated Breast Cancer Pathway |
| wikipathways | WP1993 | Angiogenesis overview |
| wikipathways | WP2011 | SREBF and miR33 in cholesterol and lipid homeostasis |
| wikipathways | WP2018 | RANKL-RANK (Receptor activator of NFKB (ligand)) Signaling Pathway |
| wikipathways | WP2032 | Human Thyroid Stimulating Hormone (TSH) signaling pathway |
| wikipathways | WP2034 | Leptin signaling pathway |
| wikipathways | WP2035 | Follicle Stimulating Hormone (FSH) signaling pathway |
| wikipathways | WP2037 | Prolactin Signaling Pathway |
| wikipathways | WP2203 | Thymic Stromal LymphoPoietin (TSLP) Signaling Pathway |
| wikipathways | WP2374 | Oncostatin M Signaling Pathway |
| wikipathways | WP2380 | Brain-Derived Neurotrophic Factor (BDNF) signaling pathway |
| wikipathways | WP244 | Alpha 6 Beta 4 signaling pathway |
| wikipathways | WP2512 | Integrated Lung Cancer Pathway |
| wikipathways | WP2571 | Polycystic Kidney Disease Pathway |
| wikipathways | WP2593 | JAK-STAT |
| wikipathways | WP2795 | Cardiac Hypertrophic Response |
| wikipathways | WP2870 | Extracellular vesicle-mediated signaling in recipient cells |
| wikipathways | WP3584 | MECP2 and Associated Rett Syndrome |
| wikipathways | WP363 | Wnt Signaling Pathway |
| wikipathways | WP3676 | BDNF-TrkB Signaling |
| wikipathways | WP3844 | PI3K-AKT-mTOR signaling pathway and therapeutic opportunities |
| wikipathways | WP3850 | Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling |
| wikipathways | WP3878 | ATM Signaling Network in Development and Disease |
| wikipathways | WP3879 | 4-hydroxytamoxifen, Dexamethasone, and Retinoic Acids Regulation of p27 Expression |
| wikipathways | WP3888 | VEGFA-VEGFR2 Signaling Pathway |
| wikipathways | WP3915 | Angiopoietin Like Protein 8 Regulatory Pathway |
| wikipathways | WP3931 | ESC Pluripotency Pathways |
| wikipathways | WP3932 | Focal Adhesion-PI3K-Akt-mTOR-signaling pathway |
| wikipathways | WP3981 | miRNA regulation of prostate cancer signaling pathways |
| wikipathways | WP4011 | Steatosis AOP |
| wikipathways | WP4018 | Pathways in clear cell renal cell carcinoma |
| wikipathways | WP4141 | PI3K-AKT-mTOR - VitD3 Signalling |
| wikipathways | WP4172 | PI3K-Akt Signaling Pathway |
| wikipathways | WP4186 | Somatroph axis (GH) and its relationship to dietary restriction and aging |
| wikipathways | WP4191 | Caloric restriction and aging |
| wikipathways | WP437 | EGF-EGFR Signaling Pathway |
| wikipathways | WP481 | Insulin Signaling |
| wikipathways | WP585 | Interferon type I signaling pathways |
| wikipathways | WP615 | Senescence and Autophagy in Cancer |
| wikipathways | WP673 | ErbB Signaling Pathway |
| smpdb | SMP00682 | Leucine Stimulation on Insulin Signaling |
| smpdb | SMP02298 | Glutaminolysis and Cancer |
| kegg | hsa04012 | ErbB signaling pathway - Homo sapiens (human) |
| kegg | hsa04066 | HIF-1 signaling pathway - Homo sapiens (human) |
| kegg | hsa04072 | Phospholipase D signaling pathway - Homo sapiens (human) |
| kegg | hsa04136 | Autophagy - other - Homo sapiens (human) |
| kegg | hsa04140 | Autophagy - animal - Homo sapiens (human) |
| kegg | hsa04150 | mTOR signaling pathway - Homo sapiens (human) |
| kegg | hsa04151 | PI3K-Akt signaling pathway - Homo sapiens (human) |
| kegg | hsa04152 | AMPK signaling pathway - Homo sapiens (human) |
| kegg | hsa04211 | Longevity regulating pathway - Homo sapiens (human) |
| kegg | hsa04213 | Longevity regulating pathway - multiple species - Homo sapiens (human) |
| kegg | hsa04218 | Cellular senescence - Homo sapiens (human) |
| kegg | hsa04371 | Apelin signaling pathway - Homo sapiens (human) |
| kegg | hsa04630 | Jak-STAT signaling pathway - Homo sapiens (human) |
| kegg | hsa04659 | Th17 cell differentiation - Homo sapiens (human) |
| kegg | hsa04714 | Thermogenesis - Homo sapiens (human) |
| kegg | hsa04910 | Insulin signaling pathway - Homo sapiens (human) |
| kegg | hsa04919 | Thyroid hormone signaling pathway - Homo sapiens (human) |
| kegg | hsa04920 | Adipocytokine signaling pathway - Homo sapiens (human) |
| kegg | hsa04930 | Type II diabetes mellitus - Homo sapiens (human) |
| kegg | hsa04931 | Insulin resistance - Homo sapiens (human) |
| kegg | hsa05165 | Human papillomavirus infection - Homo sapiens (human) |
| kegg | hsa05167 | Kaposi,s sarcoma-associated herpesvirus infection - Homo sapiens (human) |
| kegg | hsa05200 | Pathways in cancer - Homo sapiens (human) |
| kegg | hsa05205 | Proteoglycans in cancer - Homo sapiens (human) |
| kegg | hsa05206 | MicroRNAs in cancer - Homo sapiens (human) |
| kegg | hsa05210 | Colorectal cancer - Homo sapiens (human) |
| kegg | hsa05212 | Pancreatic cancer - Homo sapiens (human) |
| kegg | hsa05214 | Glioma - Homo sapiens (human) |
| kegg | hsa05215 | Prostate cancer - Homo sapiens (human) |
| kegg | hsa05221 | Acute myeloid leukemia - Homo sapiens (human) |
| kegg | hsa05224 | Breast cancer - Homo sapiens (human) |
| kegg | hsa05225 | Hepatocellular carcinoma - Homo sapiens (human) |
| kegg | hsa05226 | Gastric cancer - Homo sapiens (human) |
| kegg | hsa05230 | Central carbon metabolism in cancer - Homo sapiens (human) |
| kegg | hsa05231 | Choline metabolism in cancer - Homo sapiens (human) |
| pid | cdc42_pathway | CDC42 signaling events |
| pid | cxcr3pathway | CXCR3-mediated signaling events |
| pid | cxcr4_pathway | CXCR4-mediated signaling events |
| pid | erbb1_downstream_pathway | ErbB1 downstream signaling |
| pid | erbb2erbb3pathway | ErbB2/ErbB3 signaling events |
| pid | et_egfrpathway | EGFR-dependent Endothelin signaling events |
| pid | ifngpathway | IFN-gamma pathway |
| pid | il12_2pathway | IL12-mediated signaling events |
| pid | il2_pi3kpathway | IL2 signaling events mediated by PI3K |
| pid | il4_2pathway | IL4-mediated signaling events |
| pid | lkb1_pathway | LKB1 signaling events |
| pid | met_pathway | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
| pid | mtor_4pathway | mTOR signaling pathway |
| pid | pi3kciaktpathway | Class I PI3K signaling events mediated by Akt |
| pid | telomerasepathway | Regulation of Telomerase |
| netpath | Pathway_Alpha6Beta4Integrin | Alpha6Beta4Integrin |
| netpath | Pathway_EGFR1 | EGFR1 |
| netpath | Pathway_IL2 | IL2 |
| netpath | Pathway_KitReceptor | KitReceptor |
| netpath | Pathway_Oncostatin_M | Oncostatin_M |
| biocarta | bcellsurvivalpathway | b cell survival pathway |
| biocarta | ctcfpathway | ctcf: first multivalent nuclear factor |
| biocarta | eif4pathway | regulation of eif-4e and p70s6 kinase |
| biocarta | igf1mtorpathway | skeletal muscle hypertrophy is regulated via akt-mtor pathway |
| biocarta | mtorpathway | mtor signaling pathway |
| biocarta | stat3pathway | stat3 signaling pathway |
| reactome | R-HSA-1257604 | PIP3 activates AKT signaling |
| reactome | R-HSA-1280218 | Adaptive Immune System |
| reactome | R-HSA-162582 | Signal Transduction |
| reactome | R-HSA-1632852 | Macroautophagy |
| reactome | R-HSA-1643685 | Disease |
| reactome | R-HSA-165159 | mTOR signalling |
| reactome | R-HSA-166208 | mTORC1-mediated signalling |
| reactome | R-HSA-168256 | Immune System |
| reactome | R-HSA-194138 | Signaling by VEGF |
| reactome | R-HSA-212436 | Generic Transcription Pathway |
| reactome | R-HSA-2219528 | PI3K/AKT Signaling in Cancer |
| reactome | R-HSA-2262752 | Cellular responses to stress |
| reactome | R-HSA-3371556 | Cellular response to heat stress |
| reactome | R-HSA-3371571 | HSF1-dependent transactivation |
| reactome | R-HSA-3700989 | Transcriptional Regulation by TP53 |
| reactome | R-HSA-380972 | Energy dependent regulation of mTOR by LKB1-AMPK |
| reactome | R-HSA-388841 | Costimulation by the CD28 family |
| reactome | R-HSA-389356 | CD28 co-stimulation |
| reactome | R-HSA-389357 | CD28 dependent PI3K/Akt signaling |
| reactome | R-HSA-4420097 | VEGFA-VEGFR2 Pathway |
| reactome | R-HSA-5218920 | VEGFR2 mediated vascular permeability |
| reactome | R-HSA-5628897 | TP53 Regulates Metabolic Genes |
| reactome | R-HSA-5633007 | Regulation of TP53 Activity |
| reactome | R-HSA-5663202 | Diseases of signal transduction |
| reactome | R-HSA-5674400 | Constitutive Signaling by AKT1 E17K in Cancer |
| reactome | R-HSA-6804757 | Regulation of TP53 Degradation |
| reactome | R-HSA-6806003 | Regulation of TP53 Expression and Degradation |
| reactome | R-HSA-6807070 | PTEN Regulation |
| reactome | R-HSA-73857 | RNA Polymerase II Transcription |
| reactome | R-HSA-74160 | Gene expression (Transcription) |
| reactome | R-HSA-8943724 | Regulation of PTEN gene transcription |
| reactome | R-HSA-8953897 | Cellular responses to external stimuli |
| reactome | R-HSA-9006925 | Intracellular signaling by second messengers |
| reactome | R-HSA-9006934 | Signaling by Receptor Tyrosine Kinases |
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD119 | Temsirolimus | 5 |
| iGMDRD353 | PD0325901 | 1 |
| iGMDRD246 | NPC26 | 4 |
| iGMDRD310 | Everolimus | 28 |
| iGMDRD293 | Bleomycin | 1 |
| iGMDRD137 | Indisulam | 3 |
| iGMDRD202 | Curcumin | 1 |
| iGMDRD434 | BMS-536924 | 2 |
| iGMDRD289 | Parthenolide | 2 |
| iGMDRD88 | AICA ribonucleotide | 1 |
| iGMDRD705 | Nakiterpiosin | 6 |
| iGMDRD237 | ABT-751 | 2 |
| iGMDRD951 | mTOR kinase inhibitor | 2 |
| iGMDRD57 | Chloropentafluorobenzene | 2 |
| iGMDRD351 | GW843682X | 3 |
| iGMDRD341 | Triacsin c | 3 |
| iGMDRD945 | ML214 | 1 |
| iGMDRD154 | NSC23766 | 1 |
| iGMDRD132 | (-)-gallocatechin-3-O-gallate | 2 |
| iGMDRD123 | Isoevodiamine | 4 |
| iGMDRD901 | ELCPK | 2 |
| iGMDRD590 | AZD5363 | 2 |
| iGMDRD330 | BRD4132 | 2 |
| iGMDRD1036 | X17AAG | 1 |
| iGMDRD594 | AZD-8055 | 2 |
| iGMDRD560 | MK-2206 | 2 |
| iGMDRD399 | Selumetinib | 3 |
| iGMDRD100 | Zebularine | 2 |
| iGMDRD30 | LY-294002 | 2 |
| iGMDRD188 | Piperlongumine | 5 |
| iGMDRD268 | Cerulenin | 2 |
| iGMDRD60 | Quinoclamine | 2 |
| iGMDRD64 | Parbendazole | 3 |
| iGMDRD260 | FQI-2 | 4 |
| iGMDRD255 | SB225002 | 4 |
| iGMDRD802 | 4-methylfasudil | 2 |
| iGMDRD474 | Avrainvillamide | 6 |
| iGMDRD138 | PX 12 | 3 |
| iGMDRD187 | BRD9876 | 3 |
| iGMDRD870 | BRD63610 | 1 |
| iGMDRD61 | Kinetin riboside | 1 |
| iGMDRD152 | 179324-69-7 | 1 |
| iGMDRD193 | Fqi1 | 3 |
| iGMDRD639 | YK 4-279 | 3 |
| iGMDRD446 | LY 2183240 | 2 |
| iGMDRD796 | RapaLink-1 | 2 |
| iGMDRD778 | SCHEMBL13586708 | 15 |
| iGMDRD654 | SL 0101-1 | 1 |
| iGMDRD420 | Leucascandrolide A | 3 |
| iGMDRD433 | Lexibulin | 2 |
| iGMDRD151 | CHM-1 | 4 |
| iGMDRD126 | Tipifarnib | 4 |
| iGMDRD781 | Sirolimus | 6 |
| iGMDRD397 | Pazopanib | 3 |
| iGMDRD483 | SCH-529074 | 2 |
| iGMDRD494 | Neopeltolide | 2 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in MTOR
CLASSFICATION
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