iGMDRD119

Canonical SMILES: CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)OC(=O)C(C)(CO)CO)C)C)O)OC)C)C)C)OC

InChI: InChI=1S/C56H87NO16/c1-33-17-13-12-14-18-34(2)45(68-9)29-41-22-20-39(7)56(67,73-41)51(63)52(64)57-24-16-15-19-42(57)53(65)71-46(30-43(60)35(3)26-38(6)49(62)50(70-11)48(61)37(5)25-33)36(4)27-40-21-23-44(47(28-40)69-10)72-54(66)55(8,31-58)32-59/h12-14,17-18,26,33,35-37,39-42,44-47,49-50,58-59,62,67H,15-16,19-25,27-32H2,1-11H3

InChI Key: CBPNZQVSJQDFBE-UHFFFAOYSA-N

Standard NameCHEMBLPubchem CIDDrug StatusDrug Type
TemsirolimusCHEMBL1201182 148191AloneSmall Molecule

Drug Targets:

MTOR

Drug Pathways:

PI3K/MTOR signaling

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


Gene IDGene NameModel Num.
3845KRAS2
2475MTOR5
5241PGR1
4771NF24
11200CHEK21
5159PDGFRB1
7158TP53BP11
2033EP3001
4610MYCL1
207AKT11
7428VHL1
2064ERBB21
6850SYK1
898CCNE11
5834PYGB1
7249TSC22
57111RAB251
5290PIK3CA3
7301TYRO31
1938EEF21
2113ETS11
5728PTEN4
64321SOX171
29994BAZ2B1
7248TSC12
57103TIGAR1
5054SERPINE11
2065ERBB31
595CCND11
4629MYH111
5624PROC1

Gene in drug-gene network: Network Plot

Models in Temsirolimus

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